62. Gynecology Flashcards
CV changes in pregnancy
Increase. Plasma, erythrocytes, C.O., SV, HR, Femoral Venous pressure
Decrease. SVR, PVR
No changes. CVP, PWCP
Pulmonary changes in pregnancy
Increase. MV, RR, TV, Ins capacity, O2 comp
Decrease. Expiratory volume reserve, RV, FRC, TLC
Coagulation in pregnancy
Increase. 7, 8 , 9, 10, 12, VW
Decrease 11, 13, antithrombin III, PS
No changes 2, 5, PC
Blood gases in pregnacy
Decreased CO2 (30) HCO3 (20)
Increase pH (7.44) p50 (30)
Heart changes in pregnancy
Increase Right chamber (20%) left (10-12%), EF
New aortic / T Reg
Left hypertrophic (eccentric)
3rd trimester LIII Q small
What drug crosses placental barrier
Lidocaine
Non ionized, low MW, Lipophilic
In general, no Heparin, NDMR, Scoline, Dexm
Fetal rate system
I baseline. 110-160
II No 1 or 3
III Bradicardia, No baseline FHR, Recurrent VD/LD, sinusoidal pattern
Preeclamsia
SBP > 140 DBP > 90
After 20 weeks
Urine > 300 mg / 24h
Severe Preeclamsia
Pre +
Platelets< 100, Impaired liver function, kidney (creat > 1.1)
Right upper quadrant pain
Eclampsia
Pre + seizures
HELLP
Hemolysis + Elevated liver + low platelet
Platelets in pregnacy
Decrease 10%
Ephedrine to fetus
No changes in blood supply to the fetus.
Increase BP in the mother
Hexakapron in PPH
Improves mortality if taking in the first 3 hours
When the blood volume returns to normal after delivery
2 months
In pregnancy C.O. higher in
after delivery
Supine hypotension syndrome
Decrease MAP 10%, Increase HR 20
Decrease CO / SV 20%
8-10% pregnant
Difficult intubation and pregnancy. When the most difficult?
Immediately after delivery
VO2 higher in pregnancy
Second trimester
Pseudocholinesterase decrease after
10 weeks
BUN and creatinine in pregnancy
Decrease both
Standard bleeding after c section
1 liter
How much CO to the uterus at the end of pergnancy
10%
TEG in pregnacy
Short R
Fetal Hb compared to mature
More affinity for oxygen
Drug that produces ion trapping
Fentanyl
Blood of a term newborn
500 ml
Dural puncture epidural
No direct injection in spinal cavity but leakage from epidural to spinal
Absolute CI to neuraxial anesthesia
Some of the most important include patient
refusal, localized sepsis, and an allergy to any of the drugs planned for administration. A patient’s inability to maintain stillness during needle puncture, which can expose the
neural structures to traumatic injury, as well as raised intracranial pressure, which may theoretically predispose to brainstem herniation
Paracervical block and pain
Similar effect on pain like PCA with fentanyl
Gold standard for pain treatment after c section
Neuraxial opioids
Von W disease types
Type 1 . Lack of factor. DDAVP
Type 2. Lack of function
Type 3. Lack of function
no DDAVP to type 2b and 3