51. Chronic pain Flashcards

1
Q

Pain fibers and location

A

A delta
C
Ant horn - med/lat ST track - med/lat thalamus - somatosensory cortex

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2
Q

Opioids MoA

A

Mu, delta, Kappa receptors
G protein. Decrease Ca, CAMP, increase K

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3
Q

Opiates lambda receptors
action 4

A

Sedation, Nausea, Resp depression, constipation

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4
Q

Kappa receptors

A

Dysphoria, diuresis, sedation

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5
Q

COX 1 vs COX2

A

COX 1 Gastric protection / platelet function
COX 2 Pain Fever Bone formation

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6
Q

What receptor Naloxone blocks

A

All of them, mu, kappa and lambda

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