6 - Mitochondrial Structure/Function

Question 1

General facts about the mitochondria

Answer 1

Question 2

What is the general structure of the mitochondrion?

Answer 2

Cristae is just an invagination of the inner membrane

Question 3

Can separate components of the mitochondrion be biochemically analyzed?

Answer 3

Question 4

What is the origin of mitochondria?

Answer 4

Question 5

How do the origin and genetics of mitochondria affect them biochemically?

Answer 5

Question 6

How are mitochondrial proteins produced?

Answer 6

*

Question 7

Mitochondria can combine

Answer 7

Question 8

Mitochondrial DNA

Answer 8

Question 9

Mitochondiral genome uniqueness

Answer 9

Question 10

How does the mitochondria gain access to lipids?

Answer 10

Question 11

What does the mitochondria contribute to its genetic system?

Answer 11

Question 12

How is the mitochondria involved in apoptosis?

Answer 12

Bcl-2 family members regulate the release of proteins from the
space between the mitochondrial inner and outer membrane
and once in the cytosol, activate caspase proteases.

Question 13

How are proteins transported into the mitochondria? How is it verified?

Answer 13

Question 14

special function of the mitochondria

What is thermogenin? How does it function?

Answer 14

Question 15

How does Brown Adipose Tissue (Brown Fat) differ from normal adipose tissue?

Answer 15

Question 16

How do mitochondria respond to trauma/damage?

Answer 16

Question 17

What happens when mutations in the human mitochondrial genome occur?

Answer 17

Question 18

What is Leigh Syndrome?

Question 19

What are comon mitochondrial diseases to know?

Answer 19

Question 20

What are common features of mitochondrial DNA-associated diseased in adults?

Answer 20

Question 21

How are mitochondrial diseases diagnosed?

Answer 21

Question 22

How are mitochondrial diseases managed?

Answer 22

largely supportive