18 - Inheritance

Question 1

How can a pedigree analysis be determined most likely? What steps should you take?

Answer 1

Question 2

How can you determine the influence of genetics on disease?

Answer 2

Question 3

What are the categories of genetic disease?

Answer 3

Question 4

What is the difference between somatic and germline mutations? Do these exhibit mosaicism?

Answer 4

Somatic & Germline Mutations. Germline mutations are changes to your DNA that you inherit from the egg and sperm cells during conception. Somatic mutations are changes to your DNA that happen after conception to cells other than the egg and sperm. Mutations can lead to genetic conditions that affect your health.

Question 5

Quick overview of mendelian genetics (simple trait).

Answer 5

Question 6

Describe the mechanism of Autosomal dominant transmission and associated diseases.

Answer 6

Question 7

Describe the mechanism of Autosomal recessive transmission and associated diseases.

Answer 7

Question 8

How does cosanguinity affect mendelian inheritance?

Answer 8

Question 9

What are the similarities and differences between autosomal dominant and autosomal recessive transmission?

Answer 9

Question 10

General overview of sex linked disease.

Answer 10

Question 11

What are the similarities and differences between x-linked and y-linked transmission?

Answer 11

Question 12

What does a mitochondrial disease pedigree look like? Why?

Answer 12

mitochondria are only inherited from the mother

Question 13

What are some factors that affect “simple” inheritance making it not so simple?

Answer 13

Question 14

What are complex traits?

not as important

Answer 14