6 - Cell Division Flashcards
Humans have __ pairs of ______ chromosomes
23 pairs of homologous chromosomes
What are homologous chromosomes
Each code for the same thing, one is paternally inherited, one is maternally inherited
When 1 chromosome is replicated it makes _____ joined by a ____
A pair of chromatids joined by a centromere
What is a pair of chromatids?
2 identical chromosomes joined by a centromere
What is chromatin?
DNA wrapped around proteins called histones
What are chromosomes made from?
Chromatin (DNA and histone proteins)
What is a diploid?
Full set of chromosomes- 23 pairs of homologous chromosomes (pre pick and mix, di- 2 one from each parent)
What is a haploid?
1/2 a diploid, one chromosome inherited randomly from a parent (think pic and mix)
What are the 2 parts of the mitosis cell cycle?
Cell growth and cell division
What happens during cell growth in mitosis?
Interphase:
- cell grows in size
- synthesis of organelles
- DNA checking
- fuel stores
What happens during cell division stage in mitosis?
- mitosis
- cytokenesis
Name the stages of mitosis interphase in order
G1
S
G2
(then mitosis and cytokenesis)
What happens in G1 stage of interphase?
Cell contents (everything but chromosomes) are duplicated -cell grows in size
What does G1 checkpoint in interphase check for?
- DNA damage
- Cell size
- Cell nutrients
What is the G0 stage of interphase?
Cells leaving the cell cycle, either temp. or permanently, because of DNA damage or the cells are specialised
What is the S stage of interphase?
DNA replicated and sister cromatids form
What is the G2 stage of interphase?
Cell continues to grow in size
energy (ATP) stores replenished
What does G2 checkpoint in interphase check for?
- DNA damage
- Cell size
What happens after the G2 phase of interphase
Mitosis
BLURT! Draw the cell cycle for mitosis from G1 of interphase to cytokinesis (including checkpoints and the function of each stage)
Photo 1 in revision folder
Name the stages mitosis
Prophase, Metaphase, Anaphase, Telophase
State what happens in prophase in mitosis (5)
- chromosomes condense
- nuclear envelope dissolves
- nucleolus disappears
- centrioles produce spindles
- spindles from poles of cells attach to centromere
State what happens in Metaphase
Chromosomes are pulled to the centre, to the metaphase plate
State what happens in anaphase
Chromatids are separated, pulled to the poles of the cells