6 Flashcards

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1
Q

Tandemly repeated genes?

A

rRNA genes and histone genes

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2
Q

Repetitive sequences used as highly polymorphic genetic markers?

A

Minisattelites

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3
Q

Where are Highly repetitive sequences in chromosome?

A

Centromeric and telomeric regions

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4
Q

Polyglutamine disease?

A

Huntingtons disease, characterizes trinucleotide repeat expansion

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5
Q

VNTR?

A

Variable number of tandem repeats

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6
Q

Proteins codes by gene families?

A

Cytoskeleton and protein kinases

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7
Q

Pseudogene?

A

Members of gene families inactivated by mutations

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8
Q

Gene amplified in the genome?

A

Increase in copy number of gene in genome

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9
Q

Gene amplified in genome?

A

rRNA genes

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10
Q

Human chromosomes with Alu sequence?

A

All chromosomes

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11
Q

Retrotransposon?

A

Alu sequence

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12
Q

Main phases of cell cycle?

A

Interphase and cell division

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13
Q

Main phases of cell cycle?

A

G1(2n, diploid) , S and G2(4n, tetraploid)

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14
Q

Cell type in G0 phase?

A

Neuron

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15
Q

Processes during S phase?

A

Replication and synthesis of histones

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16
Q

Procedure where all cultured cells are in same phase?

A

Synchronization

17
Q

Methods for synchronization of cell population?

A

Serum starvation and mitotic shake-off

18
Q

Method to separate cells based on DNA content?

A

Flow cytometry

19
Q

Mitogenic substances?

A

EGF and FGF

20
Q

Component of MPF?

A

Cyclin and cyclin dependent kinase(Cdk)

21
Q

Catalytic activity in Cdk enzymes?

A

Serine specific protein kinase activity

22
Q

Major phases of mitosis?

A

Prophase
Metaphase
Anaphase
Telophase
Cytokinesis