5 Flashcards
Hexose sugars?
Glucose, galactose and fructose
Glucose polysaccharides?
Glycogen and starch
Glycosaminoglycans?
Heparan sulphate and chondroitin sulphate
Main components of nucleus?
Nuclear envelope, chromatin, nuclear matrix, nucleolus, nucleoplasma
Proteins connecting chromatin to inner surface of nuclear membrane?
Laminate proteins
Classification of heterochromatin?
Marginal, nucleolus associated and diffuse
Difference between eu and heterochromatin?
Hetero is inactive
Eu has transcriptionally active parts
Component of nucleolus?
Fibrillar center, fibrillar component, granular component, nucleolus associated heterochromatin.
Transport and G-protein that transports in the nuclear pores?
Transport- importin
G-protein- Ran
Enzyme activity of Ran?
GTPase
Types of karyopherins?
Importins and exportins
Form of DNA found in interphase and in dividing cells?
Interphase cells- Chromatin
Dividing cells- Chromosome
Chemical component of Chromatin?
DNA, RNA, ions, proteins
Chemical modifications of histones?
Phosphorylation and acetylation
Difference between constitutive and facultative heterochromatin?
Constitutive- permanently inactive
Facultative- occasionally active
Components of nucleosome?
Histone octamer and DNA
Morphological levels of chromatin organization?
Beads on a string | solenoid | looped domain | metaphase chromosome
Non histone protein with regulatory and enzymatic function?
Regulatory- TATA factor and SRF
Enzymatic- RNA polymerase and DNA polymerase
RNA molecules in chromatin?
pre-mRNA and pre-rRNA
RNP components of chromatin?
Perchromatin granules and interchromatin granules
Region of chromatids where microtubules bind?
Kinetochore
Region of chromosomes where sister chromatids attach?
Centromere
