5.3 T lymphocytes and cell mediated immunity

Question 1

where do t lymphocytes mature

Answer 1

thymus gland

Question 2

what type of immunity do t lymphocytes produce?

Answer 2

cell mediated immunity

Question 3

why does it occur

what does cell mediated immunity involve? (3)

Answer 3

• infected body cell by non-self material
• cells from other individuals of the same species
• abnormal cells

Question 4

what do TH cells have on their surfaces?

Answer 4

have receptors complimentary to a specific antigen

Question 5

what do TH cells bind to?

Answer 5

bind to antigens present on the cell surface membrane of an antigen-presenting cell

Question 6

2 examples of antigen presenting cells

Answer 6

• phagocytes presenting antigens after phagocytosis
• body cells infected by viruses/abnormal cells

Question 7

what do phagocytes present after phagocytosis that TH cells bind to?

Answer 7

antigens

Question 8

what part of TH cells bind to the antigens on antigen presenting cells?

Answer 8

complimentary receptors to the antigen

Question 9

what happens to the TH cell after the receptors bind to the antigen?

Answer 9

it activates it

Question 10

cell mediated immunity due to phagocytosis

Answer 10

• phagocytes presents antigens
• complimentary receptors on TH cells bind to antigens
• the binding activates TH cell

Question 11

what happens to after the TH cell is activated (4)

Answer 11

• become memory cells = respond rapidly to reinfection to same pathogen
• stimulate B-cells to divide = produce antibodies
• stimulate phagocyte = increases phagocytosis
• stimulate TH cells to rapidly divide by mitosis

Question 12

what does the stimulation of TH cells to divide by mitosis stimulate? (3)

Answer 12

• clones that are genetically identical
• activates TC cells
• kill infected body cells = making holes in cell membrane