5- Psychopharmacology Definitions Flashcards

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1
Q

What is a psychoactive drug?

A

An exogenous chemical not required for normal functioning, that significantly changes the cellular process of a neuron

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2
Q

What 2 changes can psychoactive drugs cause?

A

Measurable behavioural and physiological

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3
Q

What do psychoactive drugs pass through?

A

The blood-brain barrier

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4
Q

Which stages of the neurotransmitter life cycle can psychoactive drugs affect?

A

All

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5
Q

What is pharmacokinetics?

A

Study of how a drug travels within the body

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6
Q

4 processes looked at by pharmacokinetics

A

Absorption
Distribution
Metabolism
Excretion

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7
Q

What is pharmacodynamics?

A

Study of how a drug affects the body and behaviour

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8
Q

What is drug use?

A

Taking a psychoactive substance for non-medical purposes

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9
Q

What is drug abuse?

A

Drug use that leads to problems

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10
Q

What is drug dependence?

A

The situation where you need more and more of the same drug to give the good feeling

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11
Q

What is efficacy?

A

A drug’s ability to produce an effect

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12
Q

What is potency?

A

The amount of drug needed to produce an effect of a certain magnitude

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13
Q

3 ways that psychoactive drugs affect the central nervous system

A
  1. Can enhance or reduce production of enzymes so can alter how much neurotransmitter is in the synapse
  2. Can affect process of neurotransmitter binding and deactivation
  3. Can facilitate or suppress removal of neurotransmitter from synapse
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14
Q

What effect can a drug have on storage?

A

Disrupting storage

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15
Q

What effect can a drug have on production?

A

Convert a precursor

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16
Q

What effect can a drug have on release?

A

Inhibits release

17
Q

What is the agonist effect?

A

Triggers processes

18
Q

What is the antagonist effect?

A

Block receptor

19
Q

What 4 effects can a drug have on deactivation?

A

Produce more enzyme
Reduce production of enzymes so there is less removal
Disrupt reuptake
Suppress certain enzymes

20
Q

What is half-life?

A

The amount of time it takes for a drug to have 50% of its starting concentration in the blood

21
Q

What happens after one half-life?

A

Concentration of drug in the body will be half of starting dose