5 Glial Cell Biology

Question 1

What are the three type of CNS Glia?

Answer 1

(1) Macroglia
(2) Microglia
(3) Ependymal cells

Question 2

What are the two type of Macroglia?

Answer 2

Astrocytes and Oligodendrocytes

Question 3

What are the two type of PNS glia?

Answer 3

Schwann cells (neurolemmocytes) and Satellite cells

Question 4

What is the major function of Schwann cells (neurolemmocytes)?

Answer 4

Wrap around portion of only one axon to form myelin sheath

Question 5

What is the major function of Satellite cells?

Answer 5

Surround neuron cell bodies in ganglia, provide support and nutrients

Question 6

What is the major function of Microglial?

Answer 6

(1) Synaptic pruning
(2) Phagocytosis
(3) Shaping axon projection

Question 7

The spillover of glutamate from synapse are uptake by what type of glia cell?

Answer 7

Astrocytes

Question 8

What type of transporter does the Astrocytes use for glutamate uptake?

Answer 8

Na+‐dependent glutamate transporter

Question 9

Increased Na+ influx stimulates what?

Answer 9

Na,K-ATPase and associated ATP hydrolysis

Question 10

Via which protein can glial syncytium happen?

Answer 10

Connexin

Question 11

Glial syncytium among astrocytes allows spatial distribution of what substance?

Answer 11

Lactate and Na+

Question 12

Lactate is transfer to neuron via what transporters?

Answer 12

Monocarboxylate transporters

Question 13

What are the two types of myelinating glia?

Answer 13

Schwann cells and Oligodendrocytes

Question 14

Oligodendrocytes are responsible for PNS or CNS myelination?

Answer 14

CNS

Question 15

Schwann cells are responsible for PNS or CNS myelination?

Answer 15

PNS