4 Neurotransmitters and Synaptic Transmission

Question 1

Which one is faster in response speed, ligand-gated ion channels or G-protein coupled receptors?

Answer 1

Ligand-gated ion channels

Question 2

Which receptor involve Mg2+ to perform its function, AMPA receptor or NMDA receptor?

Answer 2

NMDA receptor

Question 3

Which receptor allows the influx of both Na+ and Ca2+, AMPA receptor or NMDA receptor?

Answer 3

NMDA receptor

Question 4

What is the mechanism of glutamate having its function on the metabotropic glutamate receptors (mGluRs)?

Answer 4

(1) Neurotransmitter binds to the receptor
(2) The receptor activates a G protein, causing a GTP to replace the GDP on alpha unit
(3) A G protein subunit activates an ion channel directly, or indirectly through a second messenger