16 Synaptic plasticity: transcription and protein synthesis

Question 1

What does CREB stands for?

Answer 1

cAMP-response element binding (CREB) protein

Question 2

What component are involved in the short-term sensitization in Aplysia’s presynaptic sensory neuron?

Answer 2

Neurotransmitter, secondary messengers, protein kinases, ion channels

Question 3

What neurotransmitter is involved in the short-term sensitization in Aplysia’s presynaptic sensory neuron?

Answer 3

Serotonin

Question 4

cAMP activates what in the short-term sensitization in Aplysia’s presynaptic sensory neuron?

Answer 4

PKA

Question 5

PKA phosphorylates what in the short-term sensitization in Aplysia’s presynaptic sensory neuron?

Answer 5

K+ channels,
causing the closure of them,
thus prolongs the action potentials and more influx of Ca2+ ions,
thus prolongs the action potentials and more influx of Ca2+ ions

Question 6

PKA phosphorylates what in the long-term sensitization in Aplysia’s presynaptic sensory neuron?

Answer 6

MAPK and CREB protein