10 Using human stem cell-derived neurons to study brain disorders Flashcards
Three germ layers are formed after gastrulation, what are they?
Ectoderm, Endoderm, Mesoderm
What will the Ectoderm derive into?
Neural, skin
What will the Endoderm derive into?
Lung, liver, pancreas
When isolated from the blastocyst in vitro, the cells of which part of which development stage can be maintained in culture as pluripotent embryonic stem cell (ESC) lines?
From the Inner cell mass (ICM) in Blastocyst
During the development of the embryo, the pluripotent stem cells in the ICM become increasingly restricted in their what potential?
Lineage potential
During the development of the embryo, the pluripotent stem cells in the ICM generates which kind of stem cells?
Tissue specific, multipotent stem cells