42: Drugs for UTI

Question 1

three main Abx for UTI

Answer 1

TMP-SMX, fosfomycin, nitrofurantoin

Question 2

normal flora in the urethral region

Answer 2

lactobacilli, coagulase-negative staph, corynebacterium, strep

Question 3

asymptomatic bacteriuria

Answer 3

organisms in urine but not causing illness or symptoms

Question 4

uncomplicated UTI

Answer 4

1. uncomplicated: in a healthy, non-pregnant, pre-menopausal female with normal anatomy

Question 5

recurrent UTI

Answer 5

2+ in 6 months or 3+ in 12 months

Question 6

UTI RFs

Answer 6

outflow obstruction, inadequate fluid intake, voiding dysfx, sex, spermicide, estrogen depletion, catheters, incontinence

Question 7

symptoms of acute complicated UTI

Answer 7

simple cystitis sx + fever, chills, fatigue, flank pain, pelvic pain

Question 8

RFs for MDR gram negative UTI

Answer 8

1. urine culture positive for MDR gram (-)
2. inpatient stay at healthcare facility
3. use of fluoroquinolone, TMP-SMX, or broad spectrum beta-lactam
4. travel to india, israel, spain, or mexico

Question 9

all pts with indwelling catheter develop what?

Answer 9

bacteriuria - most wont develop UTI tho, even if urine has a cloudy look with foul odor