Extras: Study Sheets Flashcards
three renal conditions associated with prune belly syndrome
- bilat hydroureteronephrosis
- VUR
- renal dysplasia
MC cause of hydronephrosis in kids
UPJ obstruction
three things that can define AKI
- Cr increase 0.3+ in 48 hours
- Cr increase 1.5x baseline in 6 hours
- urine volume <0.5ml/kg/hr x6 hours
MC cause of intrinsic AKI
ATN
four tubular & interstitial diseases to know
- ATI: acute tubular injury
- tubulointerstitial nephritis
- AD tubulointerstitial kidney disease
- Hepatorenal syndrome
tubulointerstitial nephritis
defect in tubular function but no nephrotic or nephritic syndrome
four mutations that can cause AD tubulointerstitial kidney disease
- MUC1
- UMOD
- REN
- HNF1B
treatment for overflow urinary incontinence
alpha adrenergic antagonists
associations with RTA types 1-3
1: systemic dz
2: fanconi syndrome, cystinosis, multiple myeloma
3. DM, ACEis, NSAIDs, heparin, spironolactone
ADH function
increases water reabsorption -> dilutes serum
aldosterone function
increased sodium reabsorption + K exretion
plasma HCO3, urine pH, and urine anion gap for RTA 1, 2, 3
1: low HCO3, high pH, + anion gap
2: nl HCO3, low pH, no anion gap
3. high HCO3, low pH, + anion gap
nephronophthisis
cortical tubulointerstitial damage
where are cysts in nephronophthisis?
corticomedullary junction
histo triad in nephronophthisis
- renal tubular cysts
- membrane disruption
- cell infiltrates
type of deletion associated with RCC
3p deletion
two notable histo things in papillary carcinoma
interstitial foam cells, psammoma bodies
renal tumors associated with Lynch syndrome
urothelial tumors
normal values for anion gap and osmolar gap
anion gap: <12
osmolar gap: <10
delta-delta gap normal value
if increase in AG = decrease in HCO3
normal urine anion gap value
negative number
TTP pentad of symptoms
- fever
- renal failure
- neuro sx
- hemolytic anemia
- thrombocytopenia
histo of TTP
massive ischemic necrosis in cortex only
classic sx triad of acute proliferative GN
edema, hematuria, HTN
what dz has wire loops on microscopy
SLE
one type I RPGN
goodpastures
three type 2 RPGNs
SLE, HSP, IgA nephropathy
three type 3 RPGNs
GPA, MPA, eosinophilic GPA
celiac associated with which nephritic disease
IgA nephropathy
eight nephrotic syndromes
- membranous nephropathy
- minimal change disease
- FSGS
- MPGN Type 1
- MPGN Type 2: Dense Deposit DIsease
- ALport syndrome
- BM Nephropathy
- Diabetic Nephropathy
Abs to PLA2R are found in what disease?
membranous nephropathy
what condition has tram track BM
MPGN TYpes 1 and 2
what condition has deposition of C3Nef?
Dense Deposit Disease
what condition has a basket weave appearance on histo
Alport syndrome
first sign of diabetic nephropathy
albumin in urine
what condition is due to autoimmune response to ceroid lipids
retroperitoneal fibrosis
what condition has malakoplakia and michaelis-gutmann bodies on histo?
cystitis
