4. TRANSPORT ACROSS MEMBRANES Flashcards
State the function of the cell-surface membrane
Separates two aqueous environments. Controls what goes into and out of the cell.
Describe the functions of membranes within cells
Membranes around organelles divide the cell into different compartments. They act as a barrier between organelles and the cytoplasm.
Define the term hydrophobic
Dissolves in organic solvents (does not dissolve in aqueous solutions)
Define the term hydrophilic
Dissolves in aqueous solutions
Explain why the cell-surface membrane is referred to as the fluid-mosaic model
Mosaic because they contain phospholipids and proteins, and fluid because the proteins move within the bilayer.
Describe the structure of the phospholipid bilayer
The hydrophillic head face outwards, and the hydrophobic tails face towards each other
Describe the function of cholesterol
Cholesterol affects the fluidity and increases the stability of the CSM.
Name the two types of proteins that exist within the CSM
Intrinsic and extrinsic
How would you recognise extrinsic proteins on a diagram of the CSM?
Extrinsic proteins are embedded in the outside of the bilayer
Describe the two functions of extrinsic proteins
Receptors and antigens
What are glycoproteins?
A protein with a carbohydrate group attached
What are glycolipids?
A lipid with a carbohydrate group attached
How would you recognise intrinsic proteins on a diagram of the CSM?
Intrinsic proteins are embedded within and span the CSM
Give two examples of intrinsic proteins
Carrier and channel proteins
How would you recognise a channel protein on a diagram of the CSM
It has a continuous pore all the way through
How do channel proteins transport substances?
They provide a hydrophilic passageway through the CSM
Why are channel proteins specific?
Because they are different sizes, charges and shapes, depending on the size and shape and charge of the ion or molecule
How would you recognise a carrier protein on a diagram of the CSM
It will be closed at one end
How do carrier proteins transport substances?
The molecule first binds with the carrier protein. This causes the carrier protein to change shape, transporting the molecule across the membrane.
Why are carrier proteins specific?
Each carrier protein is specific to one molecule or ion because it has a specific tertiary structure, which means it can bind to molecules with a specific shape and charge.
Name the channel protein water moves through by osmosis
Aquaporins
Name the two types of diffusion
Simple diffusion and facilitated diffusion
Why is diffusion referred to as a passive process?
It does not require ATP
Define simple diffusion
Diffusion is the net movement of molecules or ions from an area of high concentration to an area of low concentration
How will lipid-soluble substances travel through the CSM?
Simple diffusion through the phospholipid bilayer
Define facilitated diffusion
Diffusion is the net movement of molecules or ions from an area of high concentration to an area of low concentration through channel or carrier proteins
Why can small polar molecules and ions not pass through the phospholipid bilayer by simple diffusion?
They are charged
How will small polar molecules and ions travel through the CSM?
Facilitated diffusion through channel proteins
Why can large molecules not travel through the phosphoilipid bilayer by simple diffusion?
They are too large
How will large molecules and ions travel through the CSM?
Facilitated diffusion through carrier proteins
State the factors that affect the rate of simple diffusion
Surface area, concentration gradient, temperature
State the factors that affect the rate of facilitated diffusion
Surface area, concentration gradient, temperature, number of channel / carrier proteins