3p toxi: ARSÉNICO Flashcards

1
Q

⭐️unico metal pesado carcinogenico

A

arsenico PENTAVALENTE
✨era utilizado en guerra vietnam “ gas arsina o agente blue”

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2
Q

⭐️que es el HIDROARSENICISMO

A

INTOX CRONICA + FUENTE DE H20

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3
Q

⭐️MA del arsenico

A

desacopla fosforilacion oxidativa & (-) piruvato deshidrogenasa “ciclo de krebs”

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4
Q

⭐️estados en mexico donde es + comun la intox x arsenico

A

-coahuila
-veracruz
-durango

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5
Q

⭐️uso tx del arsenico

A

leucemia promielocitica

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6
Q

px llega a consulta con la siguiente sintomatologia:
-diarrea en agua de arroz
- olor a ajo
-hiperqueratosis
-hiperpigmentacion
-lineas transv blancas en uñas
-mano en garra
-anemia hemolitica
- PIE NEGRO
cual es su sospecha dx?

A

intox x arseico
*se habla de las LINEAS DE ALDRICH. MEES (lineas en uñas), SD RONNSKAR (mano en garra), HEMOLISIS

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7
Q

⭐️signos caracteristicos de una intox x arsenico

A
  • LINEAS DE ALDRICH. MEES (lineas en uñas),
  • SD RONNSKAR (mano en garra)
  • ANEMIA HEMOLITICA
  • Ca. vesical
  • ENF BOWEN (cancer)
  • pie negro
  • DIARREA EN AGUA DE ARROZ
  • HIPERPIG & HIPERQUERATOSIS
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8
Q

⭐️Dx intox x arsenico

A

orina en 24h

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9
Q

⭐️tx para intox. x arsenico agudo

A
  • BAL (dimercaprol)
    ✨cuidado con la anafilaxia en los PX ALERGICOS AL CACAHUATE
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10
Q

⭐️tx para intox. x arsenico cronico

A
  • DMPS (dimaval)
    ó
  • DMSA (succimero)
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11
Q

⭐️ aresenico mas toxico

A
  • # 1 gas arsica
  • # TRIVALENTE (1inorg, 2org) –> este lo preguntaron en el parcial
  • PENTAVALENTE se asocia a CANCER
  • organico esta ñee
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