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Histo Final > 32/33 Female Repro > Flashcards

32/33 Female Repro Flashcards

1
Q

This layer of the ovary has follicles and is highly cellularized. May also contain a corpus luteum, corpus albicans and atretic follicles

A

CORTEX

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2
Q

these cells arise in yolk sacs, migrate to ovary in embryo

A

Primordial Germ cells

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3
Q

After primordial germ cells, this forms = 2N DNA, it multiples in ovary and becomes an oocyte

A

OOGONIA

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4
Q

4n DNA and becomes arrested in PROPHASE 1, stays in ovary until puberty

A

Primary Oocytes

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5
Q

2N DNA, expelled when ovulated, arrested in metaphase 2
if fertilized it will undergo metaphase 2

A

Secondary Oocyte

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6
Q

1N DNA, Haploid

A

Mature Ovum

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7
Q

non viable daughter cells, contains DNA with minimal cytoplasm, they DIE.
All the cytoplasm goes to one big FAT OVUM

A

POLAR BODIES

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8
Q

Primary Oocyte + Surrounding Follicles Cells =

A

PRIMORDIAL Follicle

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9
Q

Only follicle to exist in ovary until puberty made up of simple squamous cells

A

PRIMORDIAL follicle

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10
Q

These follicles have a single layer of cuboidal cells

A

Primary Follicle

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11
Q

multilayered follicle cells –> granulosum cells
Zona Pellucida formed – important role in fertilization
Theca layers

A

Growing/Multilamella Follicle

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12
Q

These follicles contain fluid filled spaces = antrum in the granulosum layer

A

Antral/Secondary EARLY follicle

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13
Q

fluid filled spaces become ONE ANTRUM

A

Secondary LATE follicle

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14
Q

enormous, undergoes first meiotic division and secondary oocyte gets expelled at ovulation

A

Graafian Follicle

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15
Q

remnants of ruptured graafian follicle collapse and become converted into a temporary endocrine organ

  • secretes progesterone/estrogen

round euchromatic nuuclie and acidophilic vaculoated cytoplasm

A

CORPUS LUTEUM

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16
Q

When corpus LUTEUM degenerates due to not being implanted it gets replaced by a connective tissue scar

A

CORPUS ALBICANS

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17
Q

only one follicle reaches GRAAFIAN stage, while the rest become degenerate

A

ATRETIC FOLLICLES

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18
Q

ovaries are enlarged 2X with many follicular cysts, The tunica albuginea is thickened and the theca = hyperplastic

A

POLYCYSTIC OVARIAN SYNDROME

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19
Q

Most malignant ovarian cancers are derived from

A

SURFACE GERMINAL EPITHELIUM

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20
Q

Most common ovarian neoplasm

A

HIGH GRADE SEROUS NEOPLASM

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21
Q

funnel shaped end. opens into peritoneal cavity – has fingerlike projections that collect eggs from the ovary

A

Infundibulum Fimbria

22
Q

middle enlarged Dilated portion, common site of fertilization, with complex folds of tubal mucosa contains ciliated cells and non-ciliated secretory peg cells

A

Ampulla

23
Q

narrow segment of oviduct

A

Isthmus

24
Q

pelvic inflammatory disease

A

inflammation – salpingitis

25
Q

ectopic edometrial tissue growing in the uterine tube

A

endometriosis

26
Q

serous tubal intraepithelial carcinoma are most commonly found in ___ and ____

A

infundibulum and fimbria

27
Q

most common site of ectopic implantation and results in

A

ectopic pregnancy – tubal
rupture with hemorrhage

28
Q

The uterus is divided into:

A

endometrium, myometrium and perimetrium

29
Q

endometrium is divided into

A

stratum basalis and stratum functionalis

30
Q

this layer is supplied by SPIRAL arteries, sloughs(Sheds) at menstruation

A

Stratum Functionalis

31
Q

this layer is supplied by STRAIGHT arteries, source of proliferative stage – relatively insensitive to hormones, gland, stromal and enothelial cells multiply here

A

Stratum BASALIS

32
Q

this part of the uterus is made up of many layers of intertwined smooth muscle

A

Myometrium

33
Q

this part of the uterus is made up of the serosa, simple sqamous epithelia – supported by CT

A

Perimetrium

34
Q

this stage is ESTROGEN based = follicular
days 5-14
estrogen stimulates gland cells –> repopulate functionalis surface
ARTERIES = STRAIGHT

A

PROLIFERATIVE PHASE

35
Q

this stage is PROGESTERONE DRIVEN from corpus luteum = luteal
days 14-26
glands are tortous and enlargeed
SPIRAL arteries are LONG/COILED

A

SECRETORY STAGE

36
Q

ischemic stage
corpus luteum degenerates, progesterone decreases and spiral arteries constrict/rupture

A

Menstrual Stage

37
Q

these are common benign tumors derived from smooth muscle in the myometrium – often appear as multiple well defined white, whorled masses

A

LEIOMYOMA (FIBROIDS)

38
Q

this condition is defined by the presence of endometrial glands/stroma in locations outside the uterus – ovary, uterine tube, surfaces in peritoneal cavity (bladder and bowel)
abnormal tissue contains blood filled cysts from the “cyclical” bleeding

A

ENDOMETRIOSIS

39
Q

in this condition, the endometrial glands undergo hyperplasia

A

endometrial hyperplasia

40
Q

mucosa of CERVIX is divided into

A

endocervix and exocervix

41
Q

this portion of cervix is lined by simple COLUMNAR epithelium with mucous flands and closest to uterus proper

A

ENDOCERVIX

42
Q

this portion is lined by stratified squamous epithelia and closest to vagina

A

EXOCERVIX

43
Q

the junction between the two types of mucosa of cervix =

A

SQUAMOCOLUMNAR junction (SCJ)

44
Q

most cervical carcinomas orginate from where

A

TRANSFORMATION ZONE

45
Q

functional unit of the mammary gland =

A

Terminal Duct Lobular Unit

46
Q

at puberty, duct cells replicate giving rise to small terminal ductules with blind endings – dense connective tissue and adipose cells increase in stroma

A

INACTIVE or RESTING ADULT MAMMARY

47
Q

ducts proliferate, production of milk from secretory units of gland

A

ACTIVE MAMMARY GLAND – late pregnancy and lactation

48
Q

most breast carcinomas are derived from cells where

A

terminal duct lobular unit

49
Q

malignant proliferation of cells in ductules with no invasion of the basement membrane

A

Ductal Carcinoma in Situ

50
Q

80% of invasive carcinomas of the breast, usually grows in duct like patterns

A

Invasive Ductal Carcinoma

Histo Final (13 decks)

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