19 Flashcards

1
Q

The primitive gut is formed by the ENDODERM and is split into 3 sections:

A

Foregut
Midgut
Hindgut

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2
Q

This section of the primitive gut goes from the mouth to proximal duodenum
Gives rise to lower respriatory structures, pancreas, liver and gallbladder

A

FOREGUT

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3
Q

The foregut is supplied by

A

CELIAC TRUNK

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4
Q

This section of the primitive gut consists of rest of small intestines and proximal 2/3 of transverse colon

A

MIDGUT

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5
Q

What supplies the MIDGUT

A

SUPERIOR MESENTERIC ARTERY

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6
Q

The midgut connects to the yolk sac via what ___ which becomes incorporated into the umbilical cord

A

VITELLINE DUCT

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7
Q

This part of the primitive gut consists of the last 1/3 transverse colon to anal canal
Includes CLOACA = sewer and subdivides into two EXCRETORY passageways (urine and foodwaste)

A

HINDGUT

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8
Q

The hindgut blood supply =

A

inferior mesenteric artery

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9
Q

Closure of passage in body =

A

ATRESIA

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10
Q

Recanalization of GI tube occurs when

A

overgrowth cells die and the hollow gut tube forms again

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11
Q

Failure to reform lumen can result in

A

STENOSIS (partial reopening) and ATRESIA (complete failure to reform lumen)

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12
Q

Increased amounts of amniotic fluid =
Normal = and Pathologic =

A

POLYHYDRAMNIOS
Nromal – fetus swallows and then pees it out into amnion
Pathologic = blockage in fetal GI system

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13
Q

Development of respiratory system

A

A bud appears at week 4, growth of a SEPTI< seperates trachea and esophagus

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14
Q

Failure of a septum to properly form in development of respiratory system results in

A

tracheoesophageal fistula with an esophegeal atresia
newborn gags up milk

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15
Q

The hepatocytes, bile ducts, and epithelial lining of gall bladder develop from buds that arise out of _____ foregut

A

DISTAL foregut = future duodendum

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16
Q

Failure of biliary ducts to recanalize/develop results in _____

A

biliary atresia or stenosis

17
Q

The pancreas is made up of two buds = ___ and ____
The two buds fuse together when the foregut _____ and the pancreas is formed

A

VENTRAL and DORSAL buds
ROTATION of foregut forms pancreas

18
Q

If the ventral pancreatic bud splits and grows around both sides of duodenum, what happens to the lumen

A

it obstructs the lumen –> ANNULAR PANCREAS leading to duodental atresia and stenosis

19
Q

Congenital Pyloric Stenosis is

A

hypertrophy of smooth muscle of the pyloric sphincter which blocks movement of food into duodenum
Projectile vomiting in infant

20
Q

defective lateral folding of the embryo during weeks 3 and 4 results in

A

GASTROSCHISIS
intestines herniate through the weak ventral abdominal wall and into amniotic cavity

21
Q

MALROTATION occurs when and is what?

A

Around week 5 of midgut development and is the failure to twist properly

22
Q

The failure to properly vascularize at any point during development results in GI tube atresia or stenosis =

A

VASCULAR ACCIDENTS

23
Q

This defective seperation of the midgut occurs when the midgut loops FAIL TO RETURN to abdominal cavity weeks 6-10.
Infants are born with their intestines in an umbilical sac covered by a shiny, gray amniotic membrane

A

OMPHALOCELE

24
Q

This is the most common malformation of the small intestine
this is due to abnormal persistence of the viteline duct and its connection to the ileum

A

MECKELS DIVERTICULUM

25
Q

The dilated terminal portion of the hindgut = aka sewer

A

CLOACA

26
Q

At week 5 the cloaca becomes divided by _____ ___ and it splits into two separate passages = anorectal canal and urogenital sinus

A

URORECTAL SEPTUM

27
Q

Imperforate Anus

A

Rectal atresia = no opening, rectum ends in a blind sac d/t the anal membrane never broke down