3. Pharyngeal Arch Devel Flashcards

1
Q

3 components of the pharyngeal complex

A

CAP: cleft, arches, pouch

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2
Q

Component of the pharyngeal complex that includes skeletal, muscular, nerve, artery

A

Arch

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3
Q

Component of the pharyngeal complex that includes external features

A

Clefts

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4
Q

Component of the pharyngeal complex that includes internal features

A

Pouches

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5
Q

Neural crest cells derived from __ from arches 1-2 migrate to the face to give rise to bone and cartilage

A

Mesenchyme

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6
Q

This embryological tissue forms the facial skeleton

A

Neural crest cells

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7
Q

This embryological tissue will become posterior neurocranium and basicranium

A

Mesoderm

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8
Q

The migrating neural crest in the first arch include the formation of ___ which eventually becomes the malleus, incus, and mandible

A

Meckel’s cartilage

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9
Q

The developing face (including frontonasal and maxillary and mandibular portions) are all derived from which pharyngeal arch

A

1

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10
Q

Dorsal. To the first. Arch is an elevation formed by __ which is the sensory ganglion for nerve supplying all tissue from first arch

A

Trigeminal ganglion

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11
Q

Name for the embryological opening that will become the mouth

A

Stomodeum

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12
Q

A nasal cavity is derived from these embryological depressions

A

Nasal placodes

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13
Q

What 3 prominences need to meet for normal formation of the upper lip

A

Nasomedial, nasolateral, maxillary

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14
Q

Muscles of mastication are derived from which pharyngeal arch

A

1

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15
Q

Muscles of facial expression are derived from which pharyngeal arch

A

2

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16
Q

What muscle is a derivative of pharyngeal arch 3

A

Stylopharyngeus

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17
Q

Levator veli palatini, pharyngeal muscles, intrinsic muscles of larynx are all derived from which pharyngeal arch

A

4, 6

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18
Q

Temporalis, masseter, mylohyoid, and anterior belly of digastric are all muscles os __ and derived from pharyngeal arch __

A

Mastication, 1

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19
Q

Buccinator, orbicularis oris, posterior digastric, and platysma are all muscles of __ and derived from pharyngeal arch __

A

Facial expression, 2

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20
Q

Arch 1 features are innervated by

A

Trigeminal (V3)

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21
Q

Derivatives of arch 2 are innervated by

A

Facial nerve

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22
Q

Derivatives of arch 3 are innervated by

A

Glossopharyngeal

23
Q

Derivatives of arch 4 are innervated by

A

Vagus

24
Q

The pharyngeal region of a developing embryo surrounds the __ which will develop into upper respiratory and digestive systems

A

Foregut

25
Q

This transcription factor makes the tongue mobile and moves it out of the way so the 2 pieces of maxilla may fuse

A

Tbx22

26
Q

Signal that directs location of palatal shelves

A

Bone morphogenic proteins (BMP)

27
Q

Signal that directs early induction of facial primordia helping palatal shelves to fuse

A

Shh

28
Q

Condition where tbx22 is mutated and frenulum of tongue connects in anterior oral cavity

A

Ankyloglossia

29
Q

Separation. Or opening. In structure of. The. Face (derivatives of arch 1)

A

Oro-facial cleft

30
Q

Condition resulting in open communication between oral. And nasal cavities requiring bone grafts and orthodontic treatment

A

Complete cleft palate

31
Q

This structure carries the upper central 4 teeth and is unattached in the case of complete cleft palate, bilateral

A

Premaxilla

32
Q

When there is hypoplasia or incomplete fusion of maxillary and mandibular prominences it results in lateral facial clefts which present as large mouth also known as

A

Macrostomia

33
Q

Underdevelopment of structures associated with arch 1: downward slant to eyes, small mandible, autosomal dominant disease found on chromosome 5

A

Treacher-collins syndrome

34
Q

disease involving Severe underdevelopment of the mandible, tongue cannot move downwards and often this results in airway obstruction or cleft palate

A

Pierre robin sequence

35
Q

Cartilage that develops into the skeletal elements of arch 2

A

Reichert’s

36
Q

Stapes, styloid process, hyoid bone, and stylohyoid ligament are all derivatives of which pharyngeal arch

A

2

37
Q

Derivatives of which pharyngeal arch becomes laryngeal carilage

A

4, 6

38
Q

The first pharyngeal cleft deepens to. Form what adult. Structures

A

External auditory meatus and canal

39
Q

The first pharyngeal pouch becomes the

A

Auditory tube

40
Q

Between the first pouch and cleft lies what adult structure

A

Tympanic membrane

41
Q

Underneath the endoderm of the second pouch develops depressions and mesoderm here differentiates into lymph tissue that is called what

A

Palatine tonsils

42
Q

dorsally Pouch 3 develops into the

A

inferior Parathyroid glands

43
Q

Ventrally the 3rd pouch differentiates into

A

Thymus gland

44
Q

The 4the parathyroid gland is derived from pharyngeal pouch #___ and ends up superior to parathyroid glands 1-3

A

4

45
Q

The fourth pouch gives rise to an ultimobranchial body which differentiates into what type of cells that produce calcitonin

A

Parafollicular cells

46
Q

Chromosomal deletion with hypoparathyroidism/ hypoplastic/ absent thymus (low blood ca) resulting in immune problems, heart defects, learning difficulties

A

Digeorge syndrome

47
Q

This structure comes from pharygeal arches 1-3 and muscles of occipital somites

A

Tongue

48
Q

Base of tongue derives from which pharyngeal arch

A

Third

49
Q

Intrinsic muscles of the. Tongue innervated by.

A

Hypoglossal n.

50
Q

Posterior 1.3 of the tongue is innervated by __ n. For taste and sensation

A

Glossopharyngeal

51
Q

Anterior 2.3 of the tongue is innervated by ___ for sensation and __ for taste

A

Trigeminal, facial

52
Q

The thyroid does. Not come from a pharyngeal. Pouch but rather from a __. Forming from endoderm in the floor of the pharynx then migrates anterior to the trachea

A

Diverticulum

53
Q

Ectopic thyroid tissue can present as cysts that may rupture which is termed

A

Thyroglossal fistula