3. Hodgkin-Lymphom Flashcards

1
Q

(Hodgkin)

Epidemiologie

A

häufigste Neoplasie

bei jungen Erwachsenen

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2
Q

(Hodgkin)

Klassifikation

A

Ann-Arbor

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3
Q

(Hodgkin)

Stadium I

A

lokaler Befund

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4
Q

(Hodgkin)

Stadium II

A

eine Seite des Zwerchfells befallen

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5
Q

(Hodgkin)

Stadium III

A

beide Seite des Zwechfells befallen

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6
Q

(Hodgkin)

Stadium IV

A

disseminierter Befall

(extralymphatische Organe)

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7
Q

(Hodgkin)

Ann-Arbor-Klassifikation:

Zusatzbezeichnungen (5)

A

A: ohne B-Symptomatik

B: mit B-Symptomatik

N: nodaler Befall

E: extranodaler Befall

S: Milz

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8
Q

(Hodgkin)

prognostische Faktoren (4)

A
  • ↑ BSG
  • ≥ 3 befallene Lymphknotenareale
  • extranodaler Herd
  • großer Mediastinaltumor
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9
Q

(Hodgkin)

Leitsymptom

A

B-Symptomatik

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10
Q

(Hodgkin)

seltene, aber Hodgkin-charakteristische Symptome (3)

A
  • Pruritus
  • Alkoholschmerz
  • Pel-Ebstein-Fieber
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11
Q

(Hodgkin)

Alkoholschmerz: Lokalisation

A

in den befallenen Lymphknoten

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12
Q

(Hodgkin)

Pel-Ebstein-Fieber: Charakteristik

A

abwechselnde Fieberintervalle

und fieberfreie Intervalle

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13
Q

(Hodgkin)

Befund

A

Lymphadenopathie

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14
Q

(Hodgkin)

Lymphadenopathie: Charakteristiken (4)

A
  • derb
  • indolent
  • gummiartig
  • > 1 cm
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15
Q

(Hodgkin)

Lymphadenopathie: Lokalisationen (3)

A
  1. zervikal
  2. axillär
  3. inguinal
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16
Q

(Hodgkin)

Befunde in der Blutbild (2)

A
  • Lymphozytopenie
  • Eosinophilie
17
Q

(Hodgkin)

erhöhte Laborparameter (2)

18
Q

(Hodgkin)

Diagnosesicherung

A

Lymphknotenexstirpation

19
Q

(Hodgkin)

pathognomonisch

A

Hodgkin-Reed-Sternberg-Zellen

(HRS-Zellen)

20
Q

(Hodgkin)

häufigster Typ

A

noduläre Sklerose

21
Q

(Hodgkin)

Staging: Bildgebung (3)

A
  • Röntgen-Thorax
  • KM-CT
  • PET-CT
22
Q

(Hodgkin)

kurative Therapie

A

Radiatio + Chemotherapie

23
Q

(Hodgkin)

Chemotherapie: Schemata (2)

A

ABVD oder BEACOPP

24
Q

(Hodgkin)

Chemotherapie: Komplikation

A

maligne Zweitneoplasie