3. Hodgkin-Lymphom Flashcards

1
Q

(Hodgkin)

Epidemiologie

A

häufigste Neoplasie bei jungen Erwachsenen

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2
Q

(Hodgkin)

Klassifikation

A

Ann-Arbor

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3
Q

(Hodgkin)

Stadium I

A

lokaler Befund

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4
Q

(Hodgkin)

Stadium II

A

eine Seite des Zwerchfells befallen

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5
Q

(Hodgkin)

Stadium III

A

beide Seite des Zwechfells befallen

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6
Q

(Hodgkin)

Stadium IV

A

disseminierter Befall (extralymphatische Organe)

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7
Q

(Hodgkin)

Zusatzbezeichnungen

A

A: ohne B-Symptomatik

B: mit B-Symptomatik

N: nodaler Befall

E: extranodaler Befall

S: Milz

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8
Q

(Hodgkin)

prognostische Faktoren (2)

A
  • BSG > 50 mm/h ohne B-Symptomatik

oder

  • BSG > 30 mm/h mit B-Symptomatik
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9
Q

(Hodgkin)

Leitsymptome

A

B-Symptomatik

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10
Q

(Hodgkin)

Alkoholschmerz: Lokalisation

A

in den befallenen Lymphknoten

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10
Q

(Hodgkin)

seltene, aber Hodgkin-charakteristische Symptome (3)

A
  • Pruritus
  • Alkoholschmerz
  • Pel-Ebstein-Fieber
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11
Q

(Hodgkin)

Pel-Ebstein-Fieber: Charakteristik

A

abwechselnd Fieberintervalle (3-7d) und fieberfreie Intervalle

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12
Q

(Hodgkin)

Befund

A

Lymphadenopathie

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13
Q

(Hodgkin)

Lymphadenopathie: Charakteristiken (4)

A
  • derb
  • indolent
  • gummiartig
  • > 1 cm
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14
Q

(Hodgkin)

Lymphadenopathie: Lokalisationen (3)

A
  1. zervikal
  2. axillär
  3. inguinal
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15
Q

(Hodgkin)

Diagnosesicherung

A

Lymphknotenexstirpation

16
Q

(Hodgkin)

pathognomonisch

A

Hodgkin-Reed-Sternberg-Zellen (HRS-Zellen)

17
Q

(Hodgkin)

häufigster Typ

A

noduläre Sklerose

18
Q

(Hodgkin)

Staging: Bildgebung (4)

A
  • Abdomensonografie
  • Röntgen-Thorax
  • CT mit KM (oder MRT)
  • PET-CT
19
Q

(Hodgkin)

kurative Therapie

A

Chemotherapie + Radiatio

20
Q

(Hodgkin)

Chemotherapie: Schemata (2)

A

ABVD oder BEACOPP

21
Q

(Hodgkin)

Chemotherapie: Komplikation

A

maligne Zweitneoplasie