12. disseminierte intravasale Koagulopathie Flashcards

1
Q

(DIC)

Ätiologie (2)

A
  1. Sepsis
  2. Trauma
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2
Q

(DIC)

Pathophysiologie

A

intravasculäre Aktivierung der Gerinnungskaskade

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3
Q

(DIC)

häufigste Blutungszeichen (3)

A
  • Hämaturie
  • Hämoptysen
  • Petechien, Purpura, Ekchymosen
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3
Q

(DIC)

Leitsymptome (3)

A
  • Blutungen
  • Thrombose
  • Organversagen
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4
Q

(DIC)

häufigste Thrombose

A

TVT

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5
Q

(DIC)

häufigste Organversagen (2)

A
  • ARDS
  • akutes Nierenversagen
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6
Q

(DIC)

Score

A

DIC-Score der ISTH

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7
Q

(DIC)

DIC-Score der ISTH: Parameter (4)

A
  • Thrombozytenzahl
  • Quick-Wert
  • Fibrinogen
  • Fibrin(ogen)-Spaltprodukte oder D-Dimere oder lösliches Fibrin
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8
Q

(DIC)

Laborbefunde (4)

A
  • erniedrigte Thrombozytenzahlen
  • erniedrigte Fibrinogen-Werte
  • erhöhte Thromboplastinzeit (TPZ)
  • erhöhte Fibrin(ogen)-Spaltprodukte- oder D-Dimere- oder lösliches Fibrin-Werte
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9
Q

(DIC)

Therapie

A

supportive

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10
Q

(DIC)

Stadien (2)

A
  • frühes Stadium (thrombotischer Phänotyp)
  • spätes Stadium (fibrinolytischer Phänotyp)
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11
Q

(DIC)

Therapie thrombotischer Phänotyp (frühes Stadium)

A

Antikoagulazien

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12
Q

(DIC)

Therapie fibrinolytischer Phänotyp (spätes Stadium)

A

Substitutionstherapie

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