3 Hepatitis Viruses

Question 1

Hepatitis B Virus (HBV) Biology:

1. Virus:
2. Genome:
3. Virion:
4. Replication:

Answer 1

1. Hepadnaviridae
2. dsDNA
3. Enveloped
4. In nucleus

Question 2

Hepatitis B Virus Disease:

1. Infection:
2. Symptoms:
3. Prevention/Control:
4. Incubation

Answer 2

1. Sex, drugs
2. General malaise, anorexia, vomiting, jaundice; hepatitis, cirrhosis of liver, hepatocellular carcinoma, chronic infections (5 percent)
3. Vaccination; interferon-alpha therapy
4. 2-6 months

Question 3

Hepatitis D Virus:

1. What is it?
2. What does it require?
3. RNA genome encodes what?
4. Incubation

Answer 3

1. Subviral agent
2. Active HBV infection
3. A single protein
4. 2-6 months

Question 4

Hepatitis C Virus Biology:

1. Virus
2. Genome
3. Virion
4. Replication

Answer 4

1. Flaviviridae
2. (+)ssRNA
3. Enveloped
4. Receptor mediated endocytosis -> cytoplasm

Question 5

Hepatitis C Virus Disease:

1. Infection
2. Symptoms
3. Prevention/Treatment
4. Incubation

Answer 5

1. Sex, drugs
2. Milder than HBV, chronic infections more common, extrahepatic disease
3. No vaccine. New product, ZEPATIER for treatment
4. 2-4 months

Question 6

Hepatitis A Virus Disease:

1. Infection
2. Symptoms
3. Prevention
4. Incubation

Answer 6

1. Ingestion of recalls contaminated food/water
2. Malaise, anorexia, vomiting, jaundice
3. Vaccination
4. 2-5 weeks

Question 7

Hepatitis E Virus:

1. Infection
2. Chronic Infections?
3. Incubation
4. Similar to ___ so distinguished by ___

Answer 7

1. Foodborne/waterborne hepatitis
2. No
3. 3-6 weeks
4. HAV
   Serology