29. Flaviviridae Flashcards

1
Q

MEMBERS OF THE FAMILY FLAVIVIRADE (4 genera)

A
  1. Flavivirus
  2. Hepacivirus
  3. Pegivirus
  4. Pestivirus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which viruses have the following properties:

Virions are spherical, 40-60 nm in diameter, and consist of a tightly adherent lipid envelope covered with indistinct spikes (peplomers) surrounding a spherical nucleocapsid

Genome is a single molecule of linear, +ssRNA, approximately 11 kb (genus 1), 12.3 kb (genus 2), or approximately 9.6 kb (genus 3 and 4) in size; 5’ end capped in 1, but not 2 or 4. Genomic RNA is infectious

Cytoplasmic replication; a single polyprotein is translated from genomic RNA; it is cleaved co- and posttranslationally to yield eight or nine nonstructural proteins and three or four structural proteins

Maturation occurs on intracytoplasmic membranes without evidence of budding

A

Flavivirus

Genus1 = Flavivirus

Genus 2 = Pestivirus

Genus 3 = hepaciviruses

Genus 4 = pegiviruses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

FILL IN THE BLANKS

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

FILL IN THE BLANKS:

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

RESERVOIR HOSTS FOR GENUS PESTIVIRUS (FAM. FLAVIVIRIDAE):

Bovine viral diarrhea virus

Border disease virus

Classical swine fever virus

A
  1. Bovine viral diarrhea virus / Cattle, calves / (Contact, congenital) / Mostly inapparent. Congenital disease: generalized persistent infection, mucosal disease / Worldwide
  2. Border disease virus / Sheep / Congenital disease / Worldwide
  3. Classical swine fever virus / Swine (Contact) / Systemic disease. Congenital disease / Worldwide, but eradicated in some countries
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

MEMBERS OF GENUS PESTIVIRUS (Fam. FLAVIVIRIDAE) (3 species)

A
  1. Bovine viral diarrhea virus / Cattle, calves (Contact, congenital) / Mostly inapparent. Congenital disease: generalized persistent infection, mucosal disease / Worldwide
  2. Border disease virus / Sheep / Congenital disease / Worldwide
  3. Classical swine fever virus / Swine (Contact) / Systemic disease. Congenital disease / Worldwide, but eradicated in some countries
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

MEMBERS OF THE GENUS FLAVIVIRUS (Fam. FLAVIVIRIDAE):

mosquito-borne flaviviruses (10 species)

A
  1. Dengue viruses 1, 2, 3, and 4
  2. Japanese encephalitis virus
  3. Murray Valley encephalitis virus
  4. St. Louis encephalitis virus
  5. Tembusu virus
  6. Turkey meningoencephalitis virus
  7. Usutu virus
  8. Wesselsbron virus
  9. West Nile virus
  10. Yellow fever virus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Geographic Distribution OF GENUS PESTIVIRUS (FAM. FLAVIVIRIDAE):

  1. Bovine viral diarrhea virus
  2. Border disease virus
  3. Classical swine fever virus
A
  1. Bovine viral diarrhea virus / Cattle, calves / (Contact, congenital) / Mostly inapparent. Congenital disease: generalized persistent infection, mucosal disease / Worldwide
  2. Border disease virus / Sheep / Congenital disease / Worldwide
  3. Classical swine fever virus / Swine (Contact) / Systemic disease. Congenital disease / Worldwide, but eradicated in some countries
30
Q

Disease in Domestic Animals (or Humans) CAUSED BY GENUS PESTIVIRUS (FAM. FLAVIVIRIDAE):

  1. Bovine viral diarrhea virus
  2. Border disease virus
  3. Classical swine fever virus
A
  1. Bovine viral diarrhea virus / Cattle, calves / (Contact, congenital) / Mostly inapparent. Congenital disease: generalized persistent infection, mucosal disease / Worldwide
  2. Border disease virus / Sheep / Congenital disease / Worldwide
  3. Classical swine fever virus / Swine (Contact) / Systemic disease. Congenital disease / Worldwide, but eradicated in some countries