26. Picornaviridae Flashcards
MEMBERS OF FAMILY PICORNAVIRIDAE (10 genera)
- Aphthovirus
- Avihepatovirus
- Cardiovirus
- Enterovirus
- Erbovirus
- Kobuvirus
- Megrivirus
- Sapelovirus
- Teschovirus
- Tremovirus
Which families are included in the Order Picornavirales ? (5 families)
- Family Iflaviridae
- Family Dicistroviridae
- Family Marnaviridae
- Family Picornaviridae
- Family Secoviridae
Which viruses have the following properties:
Virions appear smooth and round in outline, are nonenveloped, <30 nm in diameter, and have icosahedral symmetry
The genome consists of a single molecule of linear, +ssRNA, 78.8 kb in size
Genomic RNA is polyadenylated at its 3’ end and has a protein, VPg, linked covalently to its 5’ end; genomic RNA is infectious
Virion RNA acts as mRNA and is translated into a polyprotein(s), which is then cleaved to yield some 11 or 12 individual proteins
Cytoplasmic replication
Picornaviruses
SPECIES OF GENUS APHTOVIRUS (FAM. PICORNAVIRIDAE) (4 species)
- Foot-and-mouth disease viruses; 7 serotypes
- Equine rhinitis A virus [Horses, camelids Systemic infection with respiratory signs]
- Bovine rhinitis A virus [Cattle Mild respiratory signs]
- Bovine rhinitis B virus [Cattle Mild respiratory signs]
SPECIES OF GENUS TREMOVIRUS (FAM. PICORNAVIRIDAE) (1 species)
- Tremovirus A [Avian encephalomyelitis virus] / Chicken, pheasant, turkey, quail / Encephalomyelitis
SPECIES OF GENUS AVIHEPATOVIRUS (FAM. PICORNAVIRIDAE) (1 species)
- Avihepatovirus A [Duck hepatitis A virus] [-Duck - Hepatitis]
SPECIES OF GENUS CARDIOVIRUS (FAM. PICORNAVIRIDAE) (3 species)
- Cardiovirus A [Encephalomyocarditis virus] / Rodents, swine, elephants, primates, mammals in contact with rodents / Encephalomyelitis and myocarditis in swine and elephants; rarely in other species; / 2 serotypes
- Cardiovirus B [Theilovirus] / Rodents Murine poliomyelitis; / 15 genotypes
- Cardiovirus C [Boone cardiovirus] / Rats / Fecal isolation
SPECIES OF GENUS ENTEROVIRUS (FAM. PICORNAVIRIDAE) (11 species)
- Enterovirus A [Human enterovirus A] / Human, simian Hand, foot-and-mouth disease, meningitis; 25 serotypes
- Enterovirus B [Human enterovirus B] / Humans Rash, respiratory disease, paralysis; 61 serotypes
- [Swine vesicular disease virus] / Swine Vesicular disease
- Enterovirus C [Human enterovirus C] / Human Poliomyelitis, Respiratory disease; 23 serotypes
- Enterovirus D / Humans, primates Respiratory disease, focal limb paralysis; 5 serotypes
- Enterovirus E [Bovine enterovirus group A] / Cattle Asymptomatic or mild enteric, respiratory, reproductive disease; 4 types
- Enterovirus F [Bovine enterovirus group B] / Cattle Asymptomatic or mild enteric, respiratory, reproductive disease; 6 types
- Enterovirus G [Porcine enterovirus B] / Swine, ovine Usually asymptomatic infection; 11 serotypes
- Enterovirus H / Simian Usually asymptomatic infection
- [Simian enterovirus A] Enterovirus J /S imian Usually asymptomatic infection; 6 types
- Rhinovirus A, B, and C [Human rhinovirus A, B, and C] / Humans Respiratory disease; 80 (A), 32 (B), and 54 (C) serotypes
SPECIES OF GENUS ERBOVIRUS (FAM. PICORNAVIRIDAE) (1 species)
- Erbovirus A [Equine rhinitis B virus] / Equine Associated with mild rhinitis
SPECIES OF GENUS KOBUVIRUS (FAM. PICORNAVIRIDAE) (3 species)
- Aichivirus A [Aichi virus] / Humans, canine, feline, rodents, birds / Gastroenteritis, enteric infections
- Aichivirus B [Bovine kobuvirus] / Ovine, bovine, ferret / Fecal detection and serum
- Aichivirus C [Porcine kobuvirus] / Swine / Fecal detection
SPECIES OF GENUS MEGRIVIRUS (FAM. PICORNAVIRIDAE) (1 species)
- Melegrivirus A / Chickens, turkeys, ducks / Fecal detection, associated with hepatitis in turkeys
SPECIES OF GENUS SAPELOVIRUS (FAM. PICORNAVIRIDAE) (3 species)
- Avian sapelovirus / Ducks / Hepatitis
- Sapelovirus A [Porcine sapelovirus/porcine enterovirus A] / Swine / Diarrhea
- Sapelovirus B [Simian sapelovirus] / Simian
SPECIES OF GENUS TESCHOVIRUS (FAM. PICORNAVIRIDAE) (1 species)
-
Teschovirus A [Porcine teschovirus] / Swine
- Type 1; encephalomyelitis
- Types 2-13; mild/asymptomatic