26. Picornaviridae Flashcards

1
Q

MEMBERS OF FAMILY PICORNAVIRIDAE (10 genera)

A
  1. Aphthovirus
  2. Avihepatovirus
  3. Cardiovirus
  4. Enterovirus
  5. Erbovirus
  6. Kobuvirus
  7. Megrivirus
  8. Sapelovirus
  9. Teschovirus
  10. Tremovirus
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2
Q

Which families are included in the Order Picornavirales ? (5 families)

A
  1. Family Iflaviridae
  2. Family Dicistroviridae
  3. Family Marnaviridae
  4. Family Picornaviridae
  5. Family Secoviridae
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3
Q

Which viruses have the following properties:

Virions appear smooth and round in outline, are nonenveloped, <30 nm in diameter, and have icosahedral symmetry

The genome consists of a single molecule of linear, +ssRNA, 78.8 kb in size

Genomic RNA is polyadenylated at its 3’ end and has a protein, VPg, linked covalently to its 5’ end; genomic RNA is infectious

Virion RNA acts as mRNA and is translated into a polyprotein(s), which is then cleaved to yield some 11 or 12 individual proteins

Cytoplasmic replication

A

Picornaviruses

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5
Q

SPECIES OF GENUS APHTOVIRUS (FAM. PICORNAVIRIDAE) (4 species)

A
  1. Foot-and-mouth disease viruses; 7 serotypes
  2. Equine rhinitis A virus [Horses, camelids Systemic infection with respiratory signs]
  3. Bovine rhinitis A virus [Cattle Mild respiratory signs]
  4. Bovine rhinitis B virus [Cattle Mild respiratory signs]
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6
Q

SPECIES OF GENUS TREMOVIRUS (FAM. PICORNAVIRIDAE) (1 species)

A
  1. Tremovirus A [Avian encephalomyelitis virus] / Chicken, pheasant, turkey, quail / Encephalomyelitis
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7
Q

SPECIES OF GENUS AVIHEPATOVIRUS (FAM. PICORNAVIRIDAE) (1 species)

A
  1. Avihepatovirus A [Duck hepatitis A virus] [-Duck - Hepatitis]
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8
Q

SPECIES OF GENUS CARDIOVIRUS (FAM. PICORNAVIRIDAE) (3 species)

A
  1. Cardiovirus A [Encephalomyocarditis virus] / Rodents, swine, elephants, primates, mammals in contact with rodents / Encephalomyelitis and myocarditis in swine and elephants; rarely in other species; / 2 serotypes
  2. Cardiovirus B [Theilovirus] / Rodents Murine poliomyelitis; / 15 genotypes
  3. Cardiovirus C [Boone cardiovirus] / Rats / Fecal isolation
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9
Q

SPECIES OF GENUS ENTEROVIRUS (FAM. PICORNAVIRIDAE) (11 species)

A
  1. Enterovirus A [Human enterovirus A] / Human, simian Hand, foot-and-mouth disease, meningitis; 25 serotypes
  2. Enterovirus B [Human enterovirus B] / Humans Rash, respiratory disease, paralysis; 61 serotypes
  3. [Swine vesicular disease virus] / Swine Vesicular disease
  4. Enterovirus C [Human enterovirus C] / Human Poliomyelitis, Respiratory disease; 23 serotypes
  5. Enterovirus D / Humans, primates Respiratory disease, focal limb paralysis; 5 serotypes
  6. Enterovirus E [Bovine enterovirus group A] / Cattle Asymptomatic or mild enteric, respiratory, reproductive disease; 4 types
  7. Enterovirus F [Bovine enterovirus group B] / Cattle Asymptomatic or mild enteric, respiratory, reproductive disease; 6 types
  8. Enterovirus G [Porcine enterovirus B] / Swine, ovine Usually asymptomatic infection; 11 serotypes
  9. Enterovirus H / Simian Usually asymptomatic infection
  10. [Simian enterovirus A] Enterovirus J /S imian Usually asymptomatic infection; 6 types
  11. Rhinovirus A, B, and C [Human rhinovirus A, B, and C] / Humans Respiratory disease; 80 (A), 32 (B), and 54 (C) serotypes
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10
Q

SPECIES OF GENUS ERBOVIRUS (FAM. PICORNAVIRIDAE) (1 species)

A
  1. Erbovirus A [Equine rhinitis B virus] / Equine Associated with mild rhinitis
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11
Q

SPECIES OF GENUS KOBUVIRUS (FAM. PICORNAVIRIDAE) (3 species)

A
  1. Aichivirus A [Aichi virus] / Humans, canine, feline, rodents, birds / Gastroenteritis, enteric infections
  2. Aichivirus B [Bovine kobuvirus] / Ovine, bovine, ferret / Fecal detection and serum
  3. Aichivirus C [Porcine kobuvirus] / Swine / Fecal detection
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12
Q

SPECIES OF GENUS MEGRIVIRUS (FAM. PICORNAVIRIDAE) (1 species)

A
  1. Melegrivirus A / Chickens, turkeys, ducks / Fecal detection, associated with hepatitis in turkeys
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13
Q

SPECIES OF GENUS SAPELOVIRUS (FAM. PICORNAVIRIDAE) (3 species)

A
  1. Avian sapelovirus / Ducks / Hepatitis
  2. Sapelovirus A [Porcine sapelovirus/porcine enterovirus A] / Swine / Diarrhea
  3. Sapelovirus B [Simian sapelovirus] / Simian
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14
Q

SPECIES OF GENUS TESCHOVIRUS (FAM. PICORNAVIRIDAE) (1 species)

A
  1. Teschovirus A [Porcine teschovirus] / Swine
    1. Type 1; encephalomyelitis
    2. Types 2-13; mild/asymptomatic
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