22. Bunyaviridae

Question 1

MEMBERS OF THE FAMILY BUNYAVIRIDAE (5 genera)

Answer 1

1. Hantavirus,
2. Nairovirus,
3. Orthobunyavirus
4. Phlebovirus,
5. Tospovirus.

Question 2

Which viruses have the following properties:

Virions are spherical, enveloped, 80-120 nm in diameter

Virions have glycoprotein spikes but no matrix protein in their envelope

Segmented -ssRNA genome; three segments—L (large), M (medium), and S (small)—total 1119 kb in size

The S segment of the genomic RNA of the member viruses of the genus 1 has an ambisense coding strategy

Cytoplasmic replication; budding into Golgi vesicles

Generally cytocidal for vertebrate cells, but noncytocidal persistent infection in invertebrate cells

Genetic reassortment occurs between closely related viruse

Answer 2

Bunyaviruses

Question 4

MEMBERS OF THE GENUS HANTAVIRUS (Fam. BUNYAVIRIDAE) (2 species)

Answer 4

• HEMORRHAGIC FEVER WITH RENAL SYNDROME (OLD WORLD) HANTAVIRUSES
• HANTAVIRUS PULMONARY SYNDROME (NEW WORLD) HANTAVIRUSES

Question 5

MEMBERS OF THE GENUS NAIROVIRUS (Fam. BUNYAVIRIDAE) (2 species)

Answer 5

NAIROBI SHEEP DISEASE VIRUS

CRIMEAN-CONGO HEMORRHAGIC FEVER VIRUS

Question 6

MEMBERS OF THE GENUS ORTHOBUNYAVIRUS (Fam. BUNYAVIRIDAE) (4 species)

Answer 6

AKABANE VIRUS

SCHMALLENBERG VIRUS

CACHE VALLEY (Cache Valley virus: rare encephalitis in humans: deer and Anopheles)

LA CROSSE and Other CALIFORNIA ENCEPHALITIS SEROGROUP VIRUSES (Main Drain virus and Shuni virus in horses)

Question 7

MEMBERS OF THE GENUS PHLEBOVIRUS (Fam. BUNYAVIRIDAE) (1 species)

Answer 7

RIFT VALLEY FEVER VIRUS