16. Birnaviridae and Picobirnaviridae Flashcards
MEMBERS OF THE FAMILY BIRNAVIRIDAE (4 genera)
Aquabirnavirus,
Avibirnavirus,
Blosnabirnavirus,
Entomobirnavirus
Which 2 viruses can Survive at 60C for 60 min and stable at pH 3 to pH 9
- Birnavirus 2. Picobirnavirus
Which 2 viruses have the following properties:
Virions of 1 are nonenveloped, hexagonal in outline, approximately 65 nm in diameter, with a single shell having icosahedral symmetry; 2 are smaller (35 nm) viruses with similar appearance.
Genome consists of two molecules of linear double-stranded RNA, designated A and B, approximately 6 kbp in overall size for 1 and 4 kbp for 2.
A single major capsid protein, and one or more nonstructural proteins (RNA polymerase (transcriptase)).
Cytoplasmic replication
- Birnavirus
- Picobirnavirus
How many serotypes have been described for infectious bursal disease virus, which one is pathogenic on which animal species?
2 serotypes (1 and 2). Only serotype 1 is pathogenic in chikens.
MEMBERS OF THE GENUS AVIBIRNAVIRUS (FAM. BIRNAVIRIDAE) (1 species)
Infectious bursal disease virus (Gumboro disease)
MEMBERS OF THE GENUS AQUABIRNAVIRUS (FAM. BIRNAVIRIDAE) (1+ species)
Infectious Pancreatic Necrosis Virus of salmonid fish, and a number of related viruses associated with infection in fish, mollusks and crustaceans.
MEMBERS OF THE GENUS BLOSNABIRNAVIRUS (FAM. BIRNAVIRIDAE) (1 species)
Blotched snakehead virus (a virus of fish)
Geographic distribution of infectious bursal disease virus (Fam. Birnaviridae) and main animal species?
Infectious bursal disease occurs worldwide in chickens, and few commercial flocks are free of the causative virus
Importance of Infectious Bursal disease virus (Fam. Birnaviridae)?
Economic consequences due to severe and prolonged immunosupression (affect pre-B lymphocytes = deficiency of B lymphocytes)
MEMBERS OF THE FAMILY PICOBIRNAVIRIDAE (1 genus)
genus Picobirnavirus
