(28) Hypersensitivity IV Flashcards

1
Q

(Type IV)

  1. Does it involve antibodies
  2. What happens in it?
  3. Do pathological effects take place earlier or later than Type !-III? how much? why?
A
  1. no, not at all
  2. T cells directly recognize foreign antigen and cause inflammation and tissure injury
  3. later; referred to as delayed (may take up to 24 hours); antigen-specific T cells haveing to increase in numbers
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2
Q

(Hypersensitivity IV)

(Contact Hypersensitivity)

  1. Highly reactive chemicals that come in contact with the skin can do what?
A
  1. modify self proteins resulting in a CD4 or CD8 T cells response

learn this graph

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3
Q

Atopic Dermatitis = type 1 hypersensitivity

Allergic Contact Dermatitis = type IV hypersensitivity

and then look at the delayed type hypersensitivity thing (on this slide)

A
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4
Q
A

D

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5
Q
A

C

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6
Q
A

B

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