(28) Hypersensitivity IV Flashcards
1
Q
(Type IV)
- Does it involve antibodies
- What happens in it?
- Do pathological effects take place earlier or later than Type !-III? how much? why?
A
- no, not at all
- T cells directly recognize foreign antigen and cause inflammation and tissure injury
- later; referred to as delayed (may take up to 24 hours); antigen-specific T cells haveing to increase in numbers
2
Q
(Hypersensitivity IV)
(Contact Hypersensitivity)
- Highly reactive chemicals that come in contact with the skin can do what?
A
- modify self proteins resulting in a CD4 or CD8 T cells response
learn this graph
3
Q
Atopic Dermatitis = type 1 hypersensitivity
Allergic Contact Dermatitis = type IV hypersensitivity
and then look at the delayed type hypersensitivity thing (on this slide)
A
4
Q
A
D
5
Q
A
C
6
Q
A
B