2.5 -- Intro to Muscles Flashcards

1
Q

What are the three types of muscles?

A

Smooth, cardiac, and skeletal

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2
Q

What is a key target of neurons?

A

Muscles

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3
Q

The functional classification of neurons is based on what?

A

Direction impulses are conducted

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4
Q

What are the two types of neurons?

A

Sensory and motor neurons

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5
Q

What is a sensory neuron?

A

Conducts impulses from the sensory receptors to the CNS

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6
Q

What is a motor neuron?

A

Conducts impulses from the CNS to target organs (Glands or muscles)

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7
Q

What does sarco mean?

A

Of the muscle

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8
Q

What is the muscle cell equivalent of the term muscle cell?

A

Muscle fiber (Myofiber)

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9
Q

What is the muscle cell equivalent of the term cell membrane?

A

Sarcolemma

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10
Q

What is the muscle cell equivalent of the term cytoplasm?

A

Sarcoplasm

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11
Q

What is the muscle cell equivalent of the term modified endoplasmic reticulum?

A

Sarcoplasmic reticulum

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12
Q

What are two characteristics of skeletal muscle?

A

Striated and voluntary

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13
Q

What has fibers that are large, multinucleate cells that appear striated under the microscope?

A

Skeletal muscle

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14
Q

What are the two characteristics of cardiac muscle?

A

Striated and involuntary

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15
Q

What has fibers that are striated but smaller, uninucleate, and branched and has cells that are joined by intercalated disks?

A

Cardiac muscle

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16
Q

What are the two characteristics of smooth muscle?

A

Smooth and voluntary

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17
Q

What has fibers that are small and lack striations?

A

Smooth muscle

18
Q

A skeletal muscle is made up of many what, which is a bundle of what?

A

Fascicle, myofibers

19
Q

What is a single cell, containing multiple bundles of contractile elements?

20
Q

What stores calcium in a muscle cell?

A

Sarcoplasmic reticulum

21
Q

What are the four parts of a myofiber?

A

Myofibril, mitochondria, sarcoplasmic reticulum, and t-tubules

22
Q

What are the nine steps of connecting an action potential to a muscle contraction in order?

Action potential produced
ACh released
Ca 2+ binds to troponin, stimulating contraction
Ca 2+ diffuses out into sarcoplasm
Action potential opens voltage-gated Ca 2+ channels
Na+ diffuses in, producing depolarizing stimulus
Binds to nicotinic ACh receptors, opens ligand-gated channels
Action potentials conducted along transverse tubules
Ca 2+ release channels in sarcoplasmic reticulum open

A

1). ACh released
2). Binds to nicotinic ACh receptors, opens ligand-gated channels
3). Na+ diffuses in, producing depolarizing stimulus
4). Action potential produced
5). Action potentials conducted along transverse tubules
6). Action potential opens voltage-gated Ca 2+ channels
7). Ca 2+ release channels in sarcoplasmic reticulum open
8). Ca 2+ diffuses out into sarcoplasm
9). Ca 2+ binds to troponin, stimulating contraction

23
Q

What are t-tubules?

A

Extensions of sarcolemma that associated with the ends of sarcoplasmic reticulum

24
Q

What do t-tubules do?

A

Bring action potential into the interior of muscle fiber

25
What activates contraction?
Calcium
26
When does calcium diffuse out of the calcium release channels (ryanodine receptors)?
Upon action potential stimulation
27
At the end of the contraction, calcium is actively pumped back into the sarcoplasmic reticulum via what?
SERCA atpase pump
28
The contractile units of a muscle are called the what?
Sarcomere
29
Thin filaments are primarily made of what?
Actin
30
Thick filaments are made of what?
Myosin
31
What are A-bands?
Where the thick and thin filaments overlap
32
What are I bands?
Where the thin filament is
33
What are H bands?
The center of A-bands where there is no thin filament overlap
34
What are Z discs?
Center of each I band
35
What is the M-line?
Protein filaments anchoring thick filaments in center
36
Contraction is when the cross bridge heads bind actin (thin filament) and pull it what?
Inward
37
What is the sliding filament mechanism?
Sarcomeres shortening during contraction as thin filaments are pulled inward
38
During contraction, what happens to the A bands?
Move closer together
39
During contraction, what happens to the I bands?
Shortens
40
During contraction, what happens to the H band?
Shortens or disappears