2.4

Question 1

List some cellular hallmarks of aging

Answer 1

• Senescence
• Inflammaging
• Decreased nutrient metabolism
• Telomere shortening
• Stem cell exhaustion

Question 2

Describe inflammaging

Answer 2

As we get older, our adaptive immune system weakens, and our innate immune system grows stronger. This leads to an increase in low-grade, non-specific, chronic inflammation, which causes tissue damage and accelerates aging.