13.3 Flashcards
1
Q
Which of somatic/germline mutations can/cannot be inherited?
A
Somatic: not inherited
Germline: can be inherited
2
Q
De novo vs inherited DNA variation
A
De novo: change occurs for the first time in a person; has not occurred in previous generations
Inherited: has occurred in previous generated; passed down to offspring
3
Q
Are epigenetic changes passed between cells in an organism? Are they ever passed to offspring?
A
- Passed between generations of cells within an organism
- Only passed on to offspring if they occur in gametes (i.e., sperm/egg)
4
Q
What is gene imprinting?
A
The process by which only the copy of a gene inherited from the mother/father is expressed in offspring
5
Q
Explain three stages at which de novo variants of an individual can arise
A
- Parent germline development (during maternal embryonic development)
- Parental aging
- Early embryonic development
