22 - Stress, Life Events, Coping Flashcards
What are the subjective sensations of stress?
Headache, nausea, fatigue, muscle tension
What are behavioural characteristics of stress?
Crying, smoking, drinking, problems concentrating
What are the health effects of stress?
CV disease, cancer, colds, skin disease, depression, weight gain/loss
What is the Yerkes-Dodson plot of relationship between arousal and performance?
Level of stress on x axis Performance on y axis 3 stages: Calm, eustress, distress Calm: - Bored - Seeing improvement Eustress: - Optimal performance found at ‘eustress’ stage - Energised, focused, work feels effortless Distress: - Fatigue, exhaustion, health, breakdown and burnout
What is eustress?
Beneficial stress
How do stress levels and health relate?
Lack of stress = boredom
Moderate levels of stress = beneficial
Too much stress = increasing ill-health
What are the physiological reactions to stress?
- Fight or flight
- General adaptation syndrome
What does the fight or flight response involve?
- Sympathetic nervous system
- Adrenal cortical system
What is the general adaptation syndrome? Who came up with it?
Selye
Three-stage process that describes the physiological changes the body goes through when under stress:
- Alarm (initial response, adrenaline)
- Resistance
- Exhaustion (chronic stress can lead to disease)
Stress can lead to decreased resistance to new stresses
What is psychoimmunology?
The study of the connections between the mind and the immune system. The basic concept of psychoimmunology is the concept that the mind and body are inseparable. It follows that stress affects the body’s ability to resist disease.
What was Cohen’s 1991 study on psychoimmunology?
Found that immune system decreased under high psychological stress:
- MRC common cold unit
- 5.8x more likely to become infected
- 2.2x more likely to get illness (cold)
What are long-term immunity effects of chronic stress?
- Increased immuno-suppression (decreased efficacy of vaccination and wound healing, decreased resistance to infection and cancer)
- Increased immuno-pathology (increased pro-inflammatory and autoimmune disease)
How can chronic stress lead to immuno-suppression?
Chronic stress decreases baseline leukocyte numbers, suppresses leukocyte function, mobilises immuno-suppresive mechanisms (e.g. reg T cells, accelerates immunosenescence
How can chronic stress lead to increased immune pathology?
Chronic stress induces increase in dysregulated, pro-inflammatory or Type-2 cytokine driven responses
How can short-term stress prove beneficial to immunity?
Increased immuno-protection
- Increased efficacy of vaccination and wound healing
- Increased resistance to infection and cancer