2010 Flashcards
- The bird and the bat wing shown opposite have bone structures that have a common origin (e.g. the bones labelled A and B in the diagram). These structures are _____________ .
a. homologous in the bird and bat
b. analogous in the bird and bat
c. homoplastic in the bird and bat
d. derived in the bird
e. derived in the ancestor of the bird
a. homologous in the bird and bat **
- Which of the following is a distinguishing feature of chordates?
a. Pharyngeal slits (at some stage of development)
b. The nerve cord
c. The ventral notochord
d. The bilaterally symmetrical body plan
e. The triploblastic body plan
a. Pharyngeal slits (at some stage of development)**
- Which ONE of the following statements is CORRECT?
a. Total body water is composed of interstitial fluid and extracellular fluid
b. The two extracellular fluid compartments of the body are interstitial fluid and plasma
c. Total body water is defined as all the fluid within the plasma membrane
d. All body cells contain intracellular fluid, except for red blood cells
e. Most body cells are in direct contact with the external environment
b. The two extracellular fluid compartments of the body are interstitial fluid and plasma **
- In a mammalian cell, which of the following solutes is at higher concentration in the intracellular fluid than in the extracellular fluid?
a. Sodium (Na+) ions
b. Potassium (K+) ions
c. Chloride (Cl-) ions
d. Bicarbonate (HCO3-) ions
e. Calcium (Ca2+) ions
b. Potassium (K+) ions **
- Which of the following is NOT a characteristic of plasma membrane transport proteins?
a. Competition
b. Selectivity
c. Saturation
d. Higher rates of transport than ion channels
e. They can move large molecules across the plasma membrane
d. Higher rates of transport than ion channels**
- Ion channels facilitate the diffusion of ions across plasma membranes. Which of the following best explains how ligand-gated channels can be opened or closed?
a. They open/close in response to membrane potential, e.g. K+ channels in muscle.
b. They open/close in response to the presence of specific molecules.
c. They open/close via interactions with subcellular proteins in the cytoskeleton of the cell e.g. change in cell shape due to muscular activity.
d. They open due to mechanical distortion of the cell.
e. They are controlled through all of the above mechanisms.
b. They open/close in response to the presence of specific molecules. **
- The following graph indicates the change in rate of galactose transport across a semipermeable membrane (by facilitated diffusion) when glucose is added to the solution.The best explanation why galactose transport drops in this situation is that _________ .
- Galactose molecules always need to go against a concentration gradient
- Galactose molecules always need to go down their concentration gradient
- Glucose competes with galactose for access to the transporter proteins
- There is reduced energy available for molecule transport
- The addition of glucose alters the osmotic pressure
Glucose competes with galactose for access to the transporter proteins **
- Homeostasis is defined as _________________ .
a. the best set of environmental conditions upon which life depends
b. the maintenance of constancy in the internal environment
c. the prevention of detrimental changes to the body’s physiological systems
d. the mechanisms of control and regulation of organs and organ system functions
e. all of the above are correct
b. the maintenance of constancy in the internal environment **
- Which ONE of the following is the BEST explanation of why adrenalin has varying effects upon different tissues?
a. Due to the presence of different receptors
b. Due to antagonistic control of different tissues
c. Because the nervous system preserves ‘fitness’ of the internal environment and will therefore only allow positive actions to occur
d. Because the different levels of activity are due to varying tonic levels of activity
e. Because adrenalin is not a very strong signal
a. Due to the presence of different receptors **
- Four organ systems exchange material between external and internal environments. Which of the following does NOT conform to this description?
a. Endocrine system
b. Gastrointestinal system
c. Reproductive system
d. Respiratory system
e. Urinary system
a. Endocrine system **
- The 200+ types of cells in the vertebrate body are divided into four general categories (tissue types). Which of the following is NOT one of these tissue types?
a. Connective tissue
b. Epithelium
c. Muscle
d. Nervous tissue
e. Integument
e. Integument **
- Which of the following is the BEST definition of tissues?
a. The smallest functional ‘unit’ able to perform life processes
b. Collections of cells performing related functions
c. Continuous, sheet-like layer of cells in combination with a thin, underlying, non-cellular, basement membrane
d. Anatomically discrete collections of different cell types that perform a single function
e. The histological view of cells
b. Collections of cells performing related functions
- Glial cells are ___________ .
a. Cells that function in metabolic support of neurons and myelin production
b. Schwann cells & oligodendrocytes
c. Cells that provide mechanical support for the basement membrane
d. Cells lining the digestive tract
e. Cells that make up nerve sheaths
a. Cells that function in metabolic support of neurons and myelin production **
- The photomicrograph ABOVE illustrates _______________ .
a. Epithelial tissue
b. Dense connective tissue
c. Loose connective tissue
d. Secretory epithelium
e. Neurons in the brain
b. Dense connective tissue
- Which ONE of the following statements is CORRECT?
a. Coronary arteries are required to provide blood supply to spongy myocardium.
b. Crocodile hearts have two aortas, allowing blood to be shunted towards the lungs during diving.
c. All endothermic homeotherms have evolved 4-chambered hearts.
d. Amphibians have two ventricles and a single atrium.
e. Fish (e.g. tuna) have single chambered hearts.
c. All endothermic homeotherms have evolved 4-chambered hearts.**
- Which one of the following anatomical structures is NOT part of the lower respiratory tract?
a. Trachea
b. Alveoli
c. Bronchi
d. Pharynx
e. Bronchioles
d. Pharynx
- Which cells are responsible for producing surfactant?
a. Goblet cells
b. Type I alveolar cells
c. Type II alveolar cells
d. Alveolar macrophages
e. None of the above
c. Type II alveolar cells
- Which ONE of the following statements best describes the muscles involved in ACTIVE EXPIRATION in mammals?
a. Diaphragm only
b. Both the diaphragm and external intercostal muscles
c. Both the diaphragm and internal intercostal muscles
d. Abdominal muscles only
e. Both the abdominal and internal intercostal muscles
e. Both the abdominal and internal intercostal muscles
- Which of the following is NOT a function of surfactant?
a. Decreases cohesive forces between water molecules.
b. Decreases work of breathing
c. Reduces surface tension
d. Prevents alveoli from collapse
e. Decreases compliance
e. Decreases compliance
- A reduction, below normal, in the number or volume of red blood cells is called ___________ .
a. Cyanosis
b. Anaemia
c. Alkalosis
d. Oedema
e. Acidosis
b. Anaemia **
- The relationship shown ABOVE describes a __________ vertebrate, which has a of _________ ml O2/g/hour.
a.
poikilotherm
3.5
b.
poikilotherm
1.5
c.
poikilotherm
1
d.
homeotherm
3.5
e.
homeotherm
1
e. homeotherm 1
- Core body temperature is regulated only a few degrees (°C) below the point at which thermal death occurs (e.g. about 42-45°C in man). Which of the choices below BEST explains why this phenomenon is likely to have evolved in vertebrates?
a. All animals have a critical thermal maximum (CTM), above which long-term exposure can be fatal.
b. The affinity of haemoglobin (Hb) for oxygen (O2) decreases for temperatures above the critical thermal maximum (CTM).
c. Above the critical thermal maximum (CTM), protein denaturation is likely to occur.
d. Physiological function is linked to the rate of biochemical processes, and therefore performance is enhanced at the higher temperatures.
e. All of the above.
d. Physiological function is linked to the rate of biochemical processes, and therefore performance is enhanced at the higher temperatures.
- Which of the following vertebrates does NOT represent an example of temporal heterothermy?
a. A hummingbird entering torpor.
b. A camel absorbing heat during the day (high Ta), dissipating the heat at night (low Ta).
c. An antelope ground squirrel making brief trips out of its burrow in order to feed.
d. An emperor penguin constricting blood flow to its legs when standing on ice, thereby reducing the temperature of its feet.
e. A squirrel undergoing hibernation.
d. An emperor penguin constricting blood flow to its legs when standing on ice, thereby reducing the temperature of its feet.
- Select the best option given below to describe the process of Selective Brain Cooling.
a. Certain species have a greater number of sweat glands over their scalp, in order to preferentially keep their brains cool.
b. Blood leaving the nasal regions (where evaporative cooling takes place) cools arterial blood before it reaches the brain via a countercurrent exchange mechanism.
c. Animals in cold environments (e.g. in Antarctic) have less insulation over their heads, in order to keep the Tbrain lower than the core temperature by increasing conductance of heat.
d. A process valuable in reducing evaporative water loss in hot environments.
e. Both b. and d.
<>e.Both b. and d.
- Select the BEST explanation to describe the pattern demonstrated in the figure ABOVE.
a. The animal is failing to maintain thermal homeostasis
b. The introduction of pyrogens to the body causes the body temperature set point to re-set at an elevated value
c. Increased insulation results in an elevated metabolism
d. Hypothermic and hyperthermic periods are part of the normal circadian fluctuations in body temperature
e. Selective brain cooling results in a cooler temperature
b. The introduction of pyrogens to the body causes the body temperature set point to re-set at an elevated value
- Consider the cell ABOVE, with intracellular and extracellular concentrations of unknown cations ‘X’ and ‘Y’ as shown. Assume that the cell membrane is permeable to both ions. Which ONE of the following statements is CORRECT?
a. The chemical (concentration) gradient for ion X+ will increase if ion Y+ is removed from the cell
b. Ion X+ will move out of the cell down its chemical (concentration) gradient
c. At the equilibrium potential for ion X+, the electrical gradient will move ion X+ into the cell
d. The equilibrium potential for ion Y+ will be negative
e. Only ion Y+ will contribute to the membrane potential of the cell
d. The equilibrium potential for ion Y+ will be negative
- Which ONE of the following statements about resting membrane potential (RMP) is CORRECT?
a. At RMP, K+ flows into the cell down its concentration gradient
b. At RMP, Na+ is at electrochemical equilibrium
c. At RMP, both K+ and Na+ flow into the cell down their electrical gradients
d. At RMP, the membrane permeability to Na+ is the same as the membrane permeability to K+
e. At RMP, the Na+/K+ ATPase pump maintains stable fluid composition by pumping Na+ into the cell and K+ out of the cell
c. At RMP, both K+ and Na+ flow into the cell down their electrical gradients
- Which ONE of the following statements is CORRECT?
a. At equilibrium potential, the net influx of all ions in a cell down their chemical gradient is equal to the net efflux of those ions down their electrical gradient
b. Membrane potential is the difference in charge between the inside and the outside of a cell, measured in millivolts.
c. An anion carries a positive charge
d. Only excitable cells have a resting membrane potential
e. Current flow across the cell membrane is entirely determined by the intracellular and extracellular concentrations of different ions
b. Membrane potential is the difference in charge between the inside and the outside of a cell, measured in millivolts.
- Consider a typical mammalian neuron sitting at resting membrane potential. Which ONE of the following statements is CORRECT?
a. Calcium influx will hyperpolarise the membrane potential
b. Chloride influx will hyperpolarise the membrane potential
c. Sodium influx will repolarise the membrane potential
d. Potassium efflux will depolarise the membrane potential
e. Influx of both calcium and chloride will hyperpolarise the membrane potential
b. Chloride influx will hyperpolarise the membrane potential
- Which ONE of the following statements about action potentials is CORRECT?
a. Threshold is the membrane potential at which regenerative opening of voltage-gated sodium channels occurs
b. Action potentials only involve active current flow
c. The repolarisation phase is associated with potassium influx
d. A stronger stimulus will produce a larger amplitude action potential
e. The depolarisation phase is caused by opening of the inactivation gate on voltage-gated sodium channels
a. Threshold is the membrane potential at which regenerative opening of voltage-gated sodium channels occurs
- Consider the diagram ABOVE and then choose ONE CORRECT statement about the cells labelled in the diagram.
a. Cells ‘A’ and ‘B’ are both oligodendrocytes, whose function is to form myelin
b. Cell ‘B’ is an astrocyte, whose main functions include supplying nutrients to neurons
c. Cell ‘C’ is an oligodendrocyte, whose main functions include forming the blood-brain barrier
d. The main function of cell ‘D’ is to clean up debris in the brain and spinal cord
e. Cell ‘E’ is a microglia, whose main function if to line the ventricles
c. Cell ‘C’ is an oligodendrocyte, whose main functions include forming the blood-brain barrier
- Consider a cell with a potassium equilibrium potential of –90 mV and a sodium equilibrium potential of +30 mV. Which ONE of the following statements is CORRECT about the movement of ions across the cell membrane?
a. At a membrane potential of –70 mV there will be net potassium movement out of the cell
b. At a membrane potential of –10 mV there will be net movement of sodium out of the cell
c. At a membrane potential of –90 mV there will be no net movement of either sodium or potassium ions
d. At a membrane potential of –30 mV there will be no net movement of either sodium or potassium ions
e. At a membrane potential of +30 mV, sodium influx will be exactly balanced by potassium efflux
a. At a membrane potential of –70 mV there will be net potassium movement out of the cell
- Consider the diagram ABOVE. The arrows indicate the direction of information flow. Which ONE of the following statements relating to the diagram is CORRECT?
a. Neuron ‘A’ is a bipolar neuron
b. Neuron ‘B’ is a central neuron
c. Neuron ‘C’ is an afferent neuron
d. Both neurons ‘A’ and ‘B’ are peripheral neurons
e. Both neurons ‘C’ and ‘B’ are efferent neurons
d. Both neurons ‘A’ and ‘B’ are peripheral neurons
b.
- Plasma is filtered from the blood and enters the renal tubule at ________.
a. A
b. B
c. C
d. D
e. E
c. C
- The process whereby fluid is removed from the tubules of the kidney via an active process is called __________ and occurs principally at region __________ .
a. Filtration C
b. Filtration E
c. Reabsorption E and D
d. Secretion E and D
e. Secretion C
c. Reabsorption E and D
- Which part of the nephron makes the renal medulla interstitium hypertonic via a counter current multiplier effect?
a. Proximal convoluted tubule A
b. Proximal convoluted tubule E
c. Loop of Henle A
d. Loop of Henle D
e. Collecting duct B
c. Loop of Henle A
a) Fill in the four empty boxes to label the four main parts of the neuron below
Box 1: Dendrites
Box 2: Soma or cell body
Box 3: Axon (the part the line is pointing to is technically a Node of Ranvier, but that isn’t a ‘main part of a neuron’ as asked for in the question, so I would probably mark it wrong, given it’s such an easy question
Box 4: Nerve terminal (or (pre)synaptic terminal or synaptic knob or synaptic bouton or synaptic button)
b) On the picture of the neuron, draw in arrows to indicate the direction of information flow through the cell.
B) Information flows from top to bottom (from dendrites –> cell body –> axon –> nerve terminal)
c) What is the primary function of the lipid-rich structure indicated by ‘A’?
C) I think ‘A’ pointed to the myelin sheath, primary function is to insulate the nerve axon and therefore increase action potential conduction velocity. May also say promote saltatory conduction.
The diagram below depicts signal transduction for SALTY tastes, with steps labelled 1 to 3.
a. Name the ion that is passing through the ion channel in Step 1
Na+ (sodium) = (sodium ions)
b. What is the effect of the ion in Step 1 on the cell membrane potential?
Depolarise
c. Name the ion involved in Step 2
Ca2+ (calcium) = (calcium ions)
d. As the result of the ion entering the cell in Step 2, what is occurring in Step 3?
Neurotransmitter release
- On the diagram below, clearly label TWO types of glial cell with their correct names.
State the main function of each of the glial cell types you identified in the diagram above. (1 mark)
Glial cell type
Function
1.
2.
