(16) G+ Flashcards
(Bacillus Anthraces)
- Disease
- Host
- Transmission
- Clinical Signs
- Path
- Diagnosis
- Treatment
- Immunity
- saprophyte in dirt - get outbreak when?
form what in high CO2?
in O2?
spores can live how long?
how different from other bacillus?
- Anthrax
- herbivores (omni a little, not carnivores)
- inhalation/ingestion of spores or cutaneous
- inhalation/ingestion –> rapid onset (2hr), bleeding (no clot), no rigor mortis
cutaneous –> Wool Sorter’s disease - stays localized - not too serious
GI form –> ulceration/fatal
- (3 toxins) from plasmid - (1) protects, binds other 2 (2) edema factor (^ CAMP), (3) lethal toxin (metalloprotease)
capsule –> avoid phags
kills phags, damage capillaries, stop clot –> vascular collapse
- Cx (no rigor/clotting, bloat)
- penicillin, tetra (before gets to LN!)
- vx
- when environment right
capsule
spores (inhibited by CO2)
100 yrs
little hemolysis
(Bacillus Cereus)
- Disease
- Host
- Path
- how diff from anthraces?
- food poisoning/ gangrenous bovine mastitis (rare)
- pigs and cows
- toxins - vessel damage, hemolysis, vomiting diarrhea
- no capsule
(Listeria Monocytogenes)
- Host
- Transmission
- Clinical Signs
- Path
- Diagnosis
- Treatment
- Immunity
- many
- fecal-oral
many food-borne (winter-spring disease)
- CNS, abortions, in humans sheep cattle
liver necrosis in turkeys
uncommon in dogs/cats
depends on point of entry - visceral: ingested/inhaled –> monogastrics –> septicemia/abortion
neural: conjuctiva, trigeminal –> circling disease in sheep/cattle
5. intra in phags, hepatocytes
depends on several enzymes (1) listerlysin O - phag mem rupture (2) PI PLC - phag mem rupture (3) ACTa - actin assembly for intra movement (4) licinthiase - cell to cell spread
- culutre CSF (elev protein), brain, placenta, aborted tissue
- penicillin/support
- vx not common
(Erysipelothrix Rhusiopathiae)
- Disease
- Host
- Transmission
- Clinical Signs
- Path
- Diagnosis
- Treatment
- Immunity
- sim to listeria how?
- Diamond Skin disease in pigs
Blue Comb in turkeys
(humans susc - stays local, sheep hoof, aquatic)
- pigs and turkeys
- found everywhere
excreted in feces/urine
- pigs
acute/chornic form - fever
skin form - necrosis/discoloarion - occlusion from immune complexes
turkeys
death from hemoorrhages on heart
5 MM of normal pigs –> stress can cause
- Cx
- penicllin/ceftiofur
- pig vx - use sim bacteria - E. tonsillarium)
- easily discolorized
(Rhodococcus Equi)
- Disease
- Host
- Transmission
- Clinical Signs
- Path
- Diagnosis
- Treatment
- Immunity
- Notes
- suppurative bronchopneumonia in young foals
- horses
- inhalation/ingestion - shed in feces
ubiquitous
- highly fatal in foals 2-6 mo
foals don’t have IFN-gamma needed for phags to work
- blocks phagolyso fusion
necrotic foci in lungs –> cough
if sputum swallowed –> enteritis
- tracheal wash, consolidated lungs on radio, PCR
- resistant to Abx in vivo
- can give Ab in vivo, but no vx
(Corynebacterium Pseudotuberculosis)
- Disease
- Host
- Transmission
- Clinical Signs
- Path
- Diagnosis
- Treatment
- Immunity
- simllar to what?
- Caseous lymphadenitis in sheep/goats
ulcerative lymphaginitis in cattle/horse
- sheep, goats, cattle, horses
- through skin from contaminated soil
- (cattle/goat/sheep)
skin –> LN of neck/lungs –> abcesses in head/neck region
(horses)
same thing but in lower pectoral limb
- Cx, smear
- lance LN, topical Abx
- no vx
- mycoplasma, cell wall has high content (resistant to phag killing)
(C. renale/C. cystidis/C. pilosum)
- Disease
- Host
- Transmission
- Clinical Signs
- Path
- Diagnosis
- Treatment
- Pizzle Rot (C. Renale in ovine)
- bovine
C. Renale -sheep
- shed in urine
- pylenonephritis & cystitis
- colonize bladder & kidneys –> thickens wall –> perm damage
(PIZZLE ROT) during high protein intake –> urea hydrolyzed –> makes end of penis ulcerative
- penicillin
