(02) Rickettsia, Ehrlichia, and Chlamydia

Question 1

(Rickettsiales - this includes neorickettsiales, ehrlichia, and anaplasma)

1. biggest commonality is what?
2. see alot of disease manifestation due to what?
3. minute - gram negative
4. transmitted by what?

Answer 1

1. replicated in leukocytes (white blood cells), RBC, or vascular endothelial cells

(most are obligate intracellular pathogens)

2. host reaction more than difference in isolates
3. arthropod vectors

Question 2

(Genus: Rickettsia)

1. rod g-
2. cell dependent obligate intracellular pathogens of eukaryotic cells (diff to culture or reach with antibiotics)
3. target cells are what?

enter hosts how?

4. most transmitted by what?

Answer 2

3. reticuloendothelial system (endothelial cells/monocytes)

phagocytosis - but escape into cytoplasm

4. arthropods

Question 3

(Order: Rickettsiales)

(Family: Anaplasmataceae)

(general characteristics)

1. arthropod and fomite vectors

Question 4

(Rickettsiales)

(Genus: Ehrlichia)

1. same as Rickettsiales
2. 1-3 weeks after exposure cause what?
3. predispose for what?
4. little what?

Answer 4

2. mild to severe leukopenias and anemias
3. secondary infections (cause thy go after white blood cells)
4. PTG