(10) Anaerobes Flashcards
1
Q
A
2
Q
- many are commensals of what?
- most are weak what?
- many genera produce what?
- many infections are what?
- WHAT ARE THE TWO MAIN CLASSES?
A
3
Q
(Obligate or Strict anaerobes)
- do not use what as final electron acceptor
- Why is this a problem?
- lack which important enzymes?
A
4
Q
- What are the main factors that should lead to suspecting an anaerobic infection?
A
- tissue necrosis, gas is present, foul odor, black discoloarion
5
Q
(Redox Potential and the growth of anaerobes)
- Eh is a measure of what?
- normal healthy tissue - Eh = ?
- as Eh gets lower - what does this mean?
- What are some conditions that can lead to lowered Eh values?
A
- redox potential
- 150 mV
- more anaerobes can grow
6
Q
rubber cork
A
7
Q
pretty sure he said we wouldn’t need to know culture stuff… but get a general idea
A
8
Q
A
9
Q
(The Clostridia)
- gram?
- very sensitive to what?
- What is the red text (the stuff he is stressing)?
A
- large, gram+ rods
10
Q
A
toxin is problem here - not so much bacteria
11
Q
(The Clostridia)
- habitat?
esp like what kinds of areas?
- normal commensals - where?
A
- ubiquitous, free-living, widely distributed in soil
esp areas with low redox potential
- oral cavity and intestinal tract
12
Q
(Clostridium Perfringens)
- Classified in A, B, C, etc… based on what?
- What is probably more widespread than any other pathogenic bacterium?
constantly present where?
A
- what type of toxin the isolate has2
- Type A
intestinal contents of humans and animals and in their environment
13
Q
(Clostridial Exotoxins)
- C. perfringens produces numerous exotoxins important in pathogenesis and classification
- What is the only one we need to know?
what is it basically?
A
- Alpha (principal lethal toxin)
phospholipase C (messes with membranes)
14
Q
(II. Non-invasive, Toxigenic Clostridia)
- produce disease strictly through action of what?
what two?
- Same mech of action - but different manifestations because of what?
A
- neurotoxins
15
Q
A
