1.5 médicaments du sytsème CV : IC Flashcards

1
Q

quels sont les autres médocs à donné en 2ème intention contre IC

A

Ivabradine
glycosides digitaliques
inhibiteurs PDE

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2
Q

quels sont les glycosides digitaliques

A

digoxine

métildigoxine

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3
Q

MA des glycosides digitaliques

A
inhibition Na+/ K+ ATP ase 
aug Na+ IC et aug Ca2+ 
IC = ionotrope + 
aug DC 
stimulation paraS réflexe : chronotrope - et dromotrope -
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4
Q

I glycosides digitaliques

A

IC grave
FA
flutter auriculaire

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5
Q

EI glycosides digitaliques

A

C : arythmies (Ca2+ élevée intoxication : bathmotrope +)
G-I : anorexie, n+, v+, d+ (action directe + réflexe vagal)
SNC : hallucinations, désorientation, perception couleurs altérée

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6
Q

interaction des glycosides digitaliques

A

kaliémie : K+ compétiteur
calcémie : aug risque arythmies
nbreux médcos : (Amidarone, Vérapamil …)

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7
Q

rem concernant les glycosides digitaliques

A

t1/2 = 36-48h et élimination rénale (marge thérapeutique faible)

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8
Q

quels sont les inhibiteurs PDE

A

milrinone

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9
Q

MA des inhibiteurs PDE

A

inhibiteurs spécifiques PDE3

aug AMPc =) inotrope + et vasodilatation a/v

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10
Q

I des inhibiteurs PDE

A

IC

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11
Q

EI des inhibiteurs PDE

A

arythmies

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12
Q

quelles sont les mesures diététiques en cas d’IC ?

A

dim apport hydrosodé

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