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Pharmaco spé tableaux > 1.13 médicaments du système CV: antithrombotiques_anticoagulants oraux > Flashcards

1.13 médicaments du système CV: antithrombotiques_anticoagulants oraux Flashcards

1
Q

quels sont les anticoagulants oraux ?

A

antagonistes vit K
inhibiteur thrombine
inhibiteur facteur Xa

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2
Q

quels sont les antagonistes vit K ?

A

Sintrom®
Marcoumar®
Warfarine (Marevan®)

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3
Q

MA des antagonistes vit K

A

Inhibition réduction vit K époxyde en hydroxyquinone nécessaire à carboxylation prothrombine, facteurs VII, IX, X, protéines C et S

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4
Q

I antagonistes vit K

A

Traitement et prévention maladies thromboemboliques

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5
Q

EI antagonistes vit K

A

Hémorragies : adapter posologie fct INR (2-3)

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6
Q

CI antagonistes vit K

A

Grossesse

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7
Q

> < antagonistes vit K

A

Aliments riches en vit K

Nombreux médicaments

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8
Q

rem concernant antagonistes vit K ?

A

Antidote : vit K

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9
Q

quels sont les inhibiteurs de la thrombine ?

A

Dabigatran

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10
Q

MA de Dabigatran

A

Inhibiteur direct thrombine

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11
Q

I de Dabigatran

A

Traitement et prévention maladies thromboemboliques

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12
Q

EI de Dabigatran

A

Hémorragies (+ risque > 75 ans)

Réactions anaphylactiques

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13
Q

CI de Dabigatran

A

IR grave, IH

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14
Q

rem concernant Dabigatran

A

Pas antidote

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15
Q

c’est quoi Dabigatran

A

anticoagulant oral de la catégorie

inhibiteur thrombine

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16
Q

quels sont les inhibiteurs du facteurs Xa ?

A

Apixaban

Rivaroxaban

17
Q

MA des inhibiteurs facteur Xa
Apixaban
Rivaroxaban

A

Inhibiteur direct

facteur Xa

18
Q

I des inhibiteurs facteur Xa
Apixaban
Rivaroxaban

A

Traitement et prévention maladies thromboemboliques

19
Q

EI des inhibiteurs facteur Xa
Apixaban
Rivaroxaban

A

Hémorragies

anémie

20
Q

rem des inhibiteurs facteur Xa
Apixaban
Rivaroxaban

A

pas antidote

21
Q

> < des inhibiteurs facteur Xa
Apixaban
Rivaroxaban

A

Substrats CYP3A4 (prudence

22
Q

rem concernant inhibiteurs facteur Xa
Apixaban
Rivaroxaban

A

pas antidote

Pharmaco spé tableaux (53 decks)

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