15. Intro to endocrinology Flashcards

1
Q

Where is atrial natriuretic peptide secreted from?

A

heart

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2
Q

function of ANP?

A

stimulates kidney to excrete for Na+ = decreased BV volume and pressure

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3
Q

which organ and cells secrete renin?

A

kidney - juxtaglomerular cells

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4
Q

function of renin

A

stimulates adrenal cortex to secrete aldosterone

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5
Q

5 basic categories of hormones

A
  1. modified AA
  2. polypeptides
  3. glycoproteins
  4. steriods
  5. fatty acid derivatives
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6
Q

what time of hormone is insulin

A

polypeptide

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7
Q

what time of hormone is testosterone

A

steriod

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8
Q

what time of hormone is prostaglandin

A

FA derivatives - eicosanoids

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9
Q

what time of hormone is FSH

A

glycoprotein

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10
Q

what time of hormone is epinephrine

A

Modified AA

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11
Q

2 hormones secreted by posterior pituitary

A
  1. oxytocin

2. ADH

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12
Q

which cells secrete ADH?

A

supraoptic nuclei

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13
Q

which cells secrete oxytocin?

A

paraventricular nuclei

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14
Q

which cells secrete GH?

A

somatotropes

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15
Q

function of ACTH

A

stimulate Adrenal medulla to produce NE and E

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16
Q

cause of goitre

A

thyroid receptor Ab = hypothyroidism

17
Q

4 functions of T4

A
  1. protein synthesis
  2. bone growth
  3. neuronal maturation
  4. cell differentiation
18
Q

function of calcitonin - and 2 ways how

A

reduce Ca2+ by bone resorption and increasing Ca2+ secretion via kidney

19
Q

function of PTH

A

increase Ca2+

20
Q

2 hormones secreted by thymus ?

A

thymopoietin

thymosin

21
Q

function of thymopoietin

A

stimulates production of T cells

22
Q

is the pancrease exocrine or endocrine

A

exocrine

23
Q

what do delta cells of islets of langerhans secrete?

A

somatostain

24
Q

2 functions of somatostatin

A
  1. inhibit release of glucagon + insulin

2. slows food absorption

25
Q

in which organ and which cells are NE and E secreted?

A

adrenal medulla - spherical chromaffin cells

26
Q

3 hormone srelease by adrenal cortex

A
  1. cortisol
  2. aldosterone
  3. androgens
27
Q

precursor for testosterone and oestrogen

A

dehydroepi-androsterone

28
Q

2 hormones secreted by ovary

A

progesterone and oestrogen

29
Q

what is gigantism caused by ?

A

increased GH in childhood

30
Q

what is acromegaly caused by?

A

increased GH in adulthood

31
Q

what is pituitary dwarfs caused by?

A

decreased GH in childhood

32
Q

cause of hyperthyroidism - graves disease?

A

autoimmune

33
Q

what is cretism caused by?

A

hypothyroidism in childhood

34
Q

what is endemic goitre caused by?

A

hypothyroidism resulting from insufficient iodine

35
Q

what is myxedema caused by?

A

hypothyroidism in adults - autoimmune

36
Q

what is addisons disease caused by?

A

hyposecretion of cortisol + aldosterone