15. Intro to endocrinology Flashcards
Where is atrial natriuretic peptide secreted from?
heart
function of ANP?
stimulates kidney to excrete for Na+ = decreased BV volume and pressure
which organ and cells secrete renin?
kidney - juxtaglomerular cells
function of renin
stimulates adrenal cortex to secrete aldosterone
5 basic categories of hormones
- modified AA
- polypeptides
- glycoproteins
- steriods
- fatty acid derivatives
what time of hormone is insulin
polypeptide
what time of hormone is testosterone
steriod
what time of hormone is prostaglandin
FA derivatives - eicosanoids
what time of hormone is FSH
glycoprotein
what time of hormone is epinephrine
Modified AA
2 hormones secreted by posterior pituitary
- oxytocin
2. ADH
which cells secrete ADH?
supraoptic nuclei
which cells secrete oxytocin?
paraventricular nuclei
which cells secrete GH?
somatotropes
function of ACTH
stimulate Adrenal medulla to produce NE and E
cause of goitre
thyroid receptor Ab = hypothyroidism
4 functions of T4
- protein synthesis
- bone growth
- neuronal maturation
- cell differentiation
function of calcitonin - and 2 ways how
reduce Ca2+ by bone resorption and increasing Ca2+ secretion via kidney
function of PTH
increase Ca2+
2 hormones secreted by thymus ?
thymopoietin
thymosin
function of thymopoietin
stimulates production of T cells
is the pancrease exocrine or endocrine
exocrine
what do delta cells of islets of langerhans secrete?
somatostain
2 functions of somatostatin
- inhibit release of glucagon + insulin
2. slows food absorption
in which organ and which cells are NE and E secreted?
adrenal medulla - spherical chromaffin cells
3 hormone srelease by adrenal cortex
- cortisol
- aldosterone
- androgens
precursor for testosterone and oestrogen
dehydroepi-androsterone
2 hormones secreted by ovary
progesterone and oestrogen
what is gigantism caused by ?
increased GH in childhood
what is acromegaly caused by?
increased GH in adulthood
what is pituitary dwarfs caused by?
decreased GH in childhood
cause of hyperthyroidism - graves disease?
autoimmune
what is cretism caused by?
hypothyroidism in childhood
what is endemic goitre caused by?
hypothyroidism resulting from insufficient iodine
what is myxedema caused by?
hypothyroidism in adults - autoimmune
what is addisons disease caused by?
hyposecretion of cortisol + aldosterone