14.1 Hormonal Communication Flashcards
What is a hormone?
A chemical messenger that is transported in the blood
What is an endocrine gland?
An organ that secretes hormones
Describe steroid hormones
- lipid soluble
- diffuse through cell surface membrane
- binds to a receptor (in cytoplasm or nucleus)
- promotes or inhibits transcription
- e.g. testosterone, oestrogen, glucocorticoids, mineralocorticoids
Describe non-steroid hormones
- hydrophilic (e.g. polypeptides or glycoproteins)
- binds to a receptor on the cell surface membrane
- activates a second messenger (e.g. cyclic AMP)
- a cascade of intracellukar reactions activates a transcription factor (for a particular gene)
- e.g. glucagon, insulin, adrenaline
Which hormones are secreted from the adrenal cortex
Glucocorticoids
Mineralocorticoids
Androgens
What is the function of the glucocorticoids?
Regulate carbohydrate metabolism
What is the function of mineralocorticoids?
To regulate salt and water concentrations
What is the function of androgens?
Various functions:
- regulation of muscle mass
- development of sexual characteristics
Which hormones or secreted from the medulla?
Adrenaline
Noradrenaline
What is the function of adrenaline?
Increases heart rate and blood glucose concentration (by stimulating glycogenolysis)
What is the function of noradrenaline?
Works in concert with adrenaline by:
- increasing heart rate
- widening airways
- increasing blood pressure