1.21 Ketogenesis, ketolysis Flashcards
1
Q
If there is no oxaloacetate for the TCA cycle…
A
AcCoA enters ketogenesis
2
Q
Localisation of ketogenesis
A
Liver (+kidney), mammary gland
Mitochondria
3
Q
Energy balance of ketogenesis
A
4
Q
Importance of ketogenesis
A
Creates additional energy store for an organism in:
- Times of starvation
- High energy demand
Ketone bodies → AcCoA → Glucose
5
Q
Draw the ketogenesis pathway
A
6
Q
Draw the ketolysis pathway
A
7
Q
Give the energy balance of ketolysis
A
8
Q
Give the biochemical function of ketones
A
Negative energy balance
- When the body needs a lot of energy e.g lactation
- GNG ↑↑↑
- OAC + AcCoA are used up → Ø TCA
9
Q
Because ketone bodies are acids:
Ketogenesis ↑ =
A
Acidosis
