1.12 Essential and non-essential amino acids Flashcards
List the essential amino acids
- Histidine
- Valine
- Lysine
- Isoleucine
- Leucine
- Phenylalanine
- Tryptophan
- Methionine
- Threonine
Give the general reaction of amino acid decarboxylation
Producing a biogenic amine

Give the degradation process of a biogenic amine
MAO = Monoamino oxidase

Degradation of Histidine
- Biogenic amine produced
- Role of the amine
Histamine
- Tissue inflammatory hormone
- Allergic reactions
Degradation of Tyrosine (DOPA)
- Biogenic amine produced
- Role of the amine
Catecholamine (Dopamine)
- Adrenaline
- Noradrenaline
Degradation of Tyrosine
- Biogenic amine produced
- Role of the amine
Tyramine
- Smooth muscle contraction
- Vasoconstrictor
Degradation of 5-OH-Trp
- Biogenic amine produced
- Role of the amine
Serotonin
- Neurotransmitter
Degradation of Glutamate
- Biogenic amine produced
- Role of the amine
GABA
- Inhibitory neurotransmitter
Degradation of Serine
- Biogenic amine produced
- Role of the amine
Ethanolamine (cholamine)
- Component of cephalin
- Acetylcholine, lecithin
Degradation of Cysteine
- Biogenic amine produced
- Role of the amine
Cysteamine
- Pantothenic acid → HS-CoA
Degradation of Cysteine acid
- Biogenic amine produced
- Role of the amine
Taurine
- Bile salt synthesis
Degradation of Aspartate
- Biogenic amine produced
- Role of the amine
β-alanine
- HS-CoA
Degradation of Ornithine
- Biogenic amine produced
Putrescine
Degradation of Lysine
- Biogenic amine produced
Cadaverine
Carnosine
- Species
- Composition
- Function
- Found in mammals
- Composition: Histidine + β-alanine
- Function:
- Muscle + Brain antioxidants
- A buffer of lactic acid
- Anti-ischemic
Anserine
- Species
- Composition
- Function
- Found in birds
- Composition: Methyl-histidine + β-alanine
- Function:
- Muscle + Brain antioxidants
- A buffer of lactic acid
- Anti-ischemic
Structure of Carnosine/Anserine

Carnosine + anserine are…
Dipeptides
Glutathione structure

Draw the biochemistry of glutathione

Give the main role of glutathione
Antioxidant
Draw the γ-glutamyl cycle
