1.19 Degradation of fatty acids: β-oxidation Flashcards
How are fatty acids transported into the mitochondrial matrix?
- Short FFA pass through the outer + inner membrane
- Long FFA pass through outer membrane, but require a carrier to pass the inner membrane
Draw the transport of long-chain FFAs into the mitochondria
CAT = Carnitine acyl transferase
![](https://s3.amazonaws.com/brainscape-prod/system/cm/279/608/698/a_image_thumb.png?1559560766)
Draw β-oxidation of even FFAs with even carbon atoms
![](https://s3.amazonaws.com/brainscape-prod/system/cm/279/608/919/a_image_thumb.png?1559560920)
Give the steps of β-oxidation of even chain FFAs
- FA-SCoA
- Trans-2-enoyl-FA-SCoA
- β-OH-FA-SCoA
- β-keto-FA-SCoA
- Fatty acyl-SCoA
Draw the pathway of odd carbon β-oxidation
![](https://s3.amazonaws.com/brainscape-prod/system/cm/279/609/633/a_image_thumb.png?1559561752)
Give the regulation of β-oxidation
![](https://s3.amazonaws.com/brainscape-prod/system/cm/279/609/093/a_image_thumb.png?1559561099)
Give the location of β-oxidation
Liver, muscle - Mitochondrial matrix
Give the energy balance of β-oxidation
![](https://s3.amazonaws.com/brainscape-prod/system/cm/279/609/211/a_image_thumb.png?1559561227)
β-oxidation of unsaturated fatty acids requires…
An extra step
Cis-β,γFA → Trans-β,γFA
Draw the reaction of Cis-β,γFA → Trans-β,γFA
![](https://s3.amazonaws.com/brainscape-prod/system/cm/279/609/354/a_image_thumb.png?1559561411)
What is the difference in the end product between odd and even carbon β-oxidation?
Even: AcCoA (Fatty acyl-SCoA)
Odd: Propionyl-CoA
The end product of odd-carbon β-oxidation is used in…
GNG
Give the energy balance of odd carbon β-oxidation
![](https://s3.amazonaws.com/brainscape-prod/system/cm/279/609/661/a_image_thumb.png?1559561787)