12/29/12 Flashcards
A male infant who is initially asymptomatic until 6-9 mos., after which he begins to experience recurrent pyogenic infections is a classic presentation for what disease?
Bruton’s agammaglubulinemia
What would you use to confirm Bruton’s agammaglobulinemia in an infant with the usual clinical presentation?
Ig lvls.
What enzyme is defective in X-linked (Bruton’s) agammaglobulinemia?
tyrosine kinase in B-cells
What immunoglobulins are decreased in transient hypoglobulinemia? By when does it usually remit?
IgG and sometimes IgM; 6-11 mos.
Why do pts w/ DiGeorge’s have seizures?
hypocalcemia
What embryonic structures are defective in DiGeorge’s syndrome?
3rd and 4th pharyngeal pouches
What is the tx for erythema migrans in children under 9?
amoxicillin for 21 days
What is the initial mgmt. of choanal atresia?
oral airway and lavage feeding
What are the 5 major Jones criteria?
carditis migratory polyarthritis Sydenham's chorea subcutaneous nodules erythema marginatum
Any male adolescent w/ epistaxis, a localizedd mass in the nasopharynx, and a bony erosion has _______ until proven otherwise.
an angiofibroma
What is the tx of pinworms?
mebendazole
Diagnose this: URI treated w/ amoxicillin, penicillin, or cephaclor. 1-2 wks later, fever, urticarial rash, polyarthralgia, and lymphadenopathy.
serum-sickness-like drug rxn
Give a short description of Legg-Calve-Perthes disease?
idiopathic avascular necrosis of the capital femoral epiphysis
A wide, fixed splitting of the 2nd heart sound is characteristic of what congenital heart defect?
ASD
What typically causes inflamed, fluctuant cervical lymph nodes?
Strep or staph infection
