1.12 — enzyme inhibition

Question 1

what are the two types of inhibitors?

Answer 1

1. reversible inhibitors — these form weak bonds (e.g. hydrogen or ionic) with the enzyme
2. irreversible inhibitors — these form strong bonds (e.g covalent) with the enzyme

Question 2

what are the two categories of inhibitors?

Answer 2

1. competitive — bind to the active site
2. non-competitive — bind away from the active site

Question 3

what are competitive inhibitors?

Answer 3

inhibitors that bind to the active site

Question 4

what are non competitive inhibitors

Answer 4

bind away from the active site

Question 5

how do competitive inhibitors inhibit?

Answer 5

bind to the active site to prevent enzyme-substrate complexes

Question 6

how does competitive inhibition work?

Answer 6

1. competitive inhibitors have a similar shape to the substrate mewing