1.1.2 DT Anti Anxiety Drugs (Bi) Flashcards
Give examples of anxiety disorders:
- phobias
- obsessive compulsive disorder
- generalised anxiety disorders
- post-traumatic stress disorder
What does an an anxiety disorder involve?
Continued worry of fear that worsens over time
What drugs can be used to treat anxiety disorders?
- benzodiazepines
* beta blockers
What is a benzodiazepine and when is it used?
It is a type of sedative sometimes used by severe periods of anxiety as they help ease symptoms within 30-90 minutes of taking the drugs
How do benzodiazepines work?
enhancing the action of the neurotransmitter GABA, found in high concentrations in the cortex and limbic system.
GABA reduces the excitability of neurons thus having a calming effect on the human brain
What are the side effects of benzodiazepines?
- sleepiness
- problems with memory
- problems with concentration
- headaches
- tremors
What is the main issue of benzodiazepines?
They are highly addictive and as a result can’t be used for more than four weeks at a time
What is a beta blocker, what does it do and when is it used?
- a drug used to decrease the activity of the heart by blocking the action of hormones such as adrenaline and noradrenaline
- commonly used to treat heart conditions
- also used to treat the physical symptoms of anxiety
What are the physical symptoms of anxiety beta blockers treat?
- shaking
- trembling
- blushing
- heartbeat
What do beta blockers block?
The release of the stress hormones adrenaline and noradrenaline in some areas of the body
What does using beta blockers result in?
Decease in heart rate and blood pressure
What are the common side effects of beta blockers?
- dizziness
- tiredness
- blurred vision
- cold hands and feet
What are the less common side effects of beta blockers?
- insomnia
* depression
What did Kahn et al study?
The effectiveness of benzodiazepines in comparison to a placebo group
How did Kahn et al carry out the research?
- scientific manner (no researcher bias)
- followed 250 patients over 8 weeks
- 2 groups (placebo) and (BZ)