10.1 Cell Cycle Flashcards
What is the steps of the cell cycle
G1, G0 if needed, S, G2, M (G1, S, and G2 are interphase)
What happens at G1
The cell increases in size and prepares to replicate its DNA
What is the purpose of G0
To stop cells that do pass the checkpoint from continuing the cell cycle.
What happens at S
The cell Replicates its DNA
What happens at G2
The cell continues to grow and prepares for division
What happens at M
Mitosis continues and produces 2 daughter cells
Stimulatory proteins
Growth factors, CDK-proteins, mitotic cyclins, cyclosome
What are stimulatory proteins
Proteins that will help the cells through the process of the cell cycle
Inhibitory proteins
p53, retinoblastoma protein (RBP), ataxia telangiectasia mutated (ATM), breast cancer 1, mitotic arrest deficient
What are inhibitory proteins
Proteins that inactivate CDK-cyclins or prevent their activation
What are proto-oncogenes
Mutated proto-oncogenes who increase stimulation.
What are tumor suppressor genes
They cause a loss of inhibition. When on of the alleles is present suppressors only partially slow, When both are present suppressors wont be produced.