1-31 notecards333 Flashcards
What vitamins must be analyzed for patients with neuropsychiatric symptoms?
B12 and B9
Clozapine or Carbamazepine must be monitored for what?
Agranulocytosis, low WBC, will show up as a severe throat infection
Clozapine look out for agranulocytosis, which a severe form of ___________.
Leukopenia
What is a first line drug for treating bipolar disorder? What two organs must be examined?
Lithium, look at thyroid and kidney
Lithium has a narrow what? Drug kinetics
Narrow therapeutic range
DST or dexamethasone suppression testing show what type of system problems?
Endocrine disturbances
When there is high and low cortisol, what is it?
High is Cushing Disease
Low is Addison’s Disease
What does Dexamethasone (synthetic cortisol) suppress resulting in suppression of adrenal cortisol?
ACTH, body uses that as a negative feedback loop
About half the patients with major depressive disorder have a positive what?
DST, that is the usual suppression of cortisol is limited
Patients with a positive DST, will respond well to what?
Antidepressant agents or electroconvulsive therapy
Positive Dexamethasone suppression test is not specific to what?
Major depressive disorder
If not depression, what other things can trigger an abnormal thyroid function test?
Mimic depression and anxiety
Neonatal hypothyroidism results in what?
Mental Retardation/intellectual disability
Hypothyroidism may have what type of symptoms that indicates depression?
weakness, stiffness, poor appetite, constipation, menstrual abnormalities, slowed speech, apathy, impaired memory, and even hallucinations and delusions.
Large Goiter, bulging eyes, scaly plaques is what type of hyperthyroidism?
Grave’s Disease
What are symptoms of the hyperthyroidism?
Tachycardia, palpitations, heat tolerance, elevated TSH, free T4, the autonomic nervous system is overactive
What is a state of everything slows down, weak, walk with a shuffle, reflexes are slow, intolerant of cold, slowed heart rate and constipation, less sympathetic activation?
Hypothyroidism
Decreased sweating, muscle cramps, joint pain, bradycardia/decreased cardiac output?
Hypothyroidism
What is a specific form of cutaneous edema, hypothyroidism?
Myxedema
Myxedema is really what kind of disturbance? What are other symptoms?
Connective tissue
Peripheral edema, deepened voice, and elevated proteoglycans/GAG