032 Allergy and Hypersensitivity Flashcards
Explain type I hypersinsitivity
IgE mediated
Granules contain histamine, prostaglandines, leukotrines, serotonin etc.
Explain type II hypersinsitivity
When antibody recognises self antigens
Explain type III hypersinsitivity
When immune complexes are not cleared up in the blood, activating complement cascade
Explain type Iv hypersinsitivity
T-cell mediated
Explain type V hypersinsitivity
Stimulatory
Which hypersensitivity is Graves disease?
Type V
Which hypersensitivity is toxic shock syndrome?
Innate hypersensitivity
Which sensitivity is Alzheimers and how does it occur?
Innate hypersensitivity - low grade chronic activation
What sensitivity is lupus?
Type III
What sensitivity is rheumatoid arthritis?
Type iII
What sensitivity is goodpastures syndrome?
Type II
What sensitivity is hemolytic newborn disease?
Type II
What sensitivity is eczema?
Type I
Why do peanut allergies become systemic?
Soluble in fats to be transported