029 Autoimmunity

Question 1

What is Hashiomoto disease?

Answer 1

Hypothyroidism - autoantibodies against thyroglobulin and thyroid peroxidase.

Question 2

What is Myaethenia gravis?

Answer 2

Autoantibodies against ACh receptors blocking transmission of nerve impulses at motor end plate junctions.

Question 3

What is Graves disease?

Answer 3

Hyperthyroidism - autoantibodies against thyroid stimulating hormone

Question 4

What is multiple sclerosis?

Answer 4

Autoantibodies against myelin basic protein

Question 5

What is pernicious anaemia?

Answer 5

Autoantibodies against intrinsic factor or parietal cells

Question 6

What is goodpasteurs syndrome?

Answer 6

Autoantibodies against those in the lungs or the kidney

Question 7

What is type I diabetes

Answer 7

Autoantibodies against beta islet of langerhan cells in the pancreas

Question 8

What is systemic lupus erythematosus?

Answer 8

Autoanitbodies against double stranded dna

Question 9

What is Rheumatoid artheritis?

Answer 9

Autoantibodies against Fc part of the IgG molecule, which is deposited in joints leading to chronic inflammatory response, destroying tissue.

Question 10

How does polio cause autoimmunity?

Answer 10

It has antigen similar to the one of ACh. Causing myasthemia gravis.